ArticleChemistryOpen2016
Novel Natural Oximes and Oxime Esters with a Vibralactone Backbone from the Basidiomycete Boreostereum vibrans.
Article in ChemistryOpen, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Pyrimidine-containing natural products: occurrences and biological activities.Natural products and bioprospecting · 2026Review
- Direct vicinal sulfonyloximation of alkenes: an efficient and straightforward approach towards the synthesis of α-sulfonyl ketoximes.RSC advances · 2025Review
- Vibralactone derivatives isolated from co-cultures of the basidiomycetes Stereum hirsutum and Boreostereum vibrans.Natural products and bioprospecting · 2025Article
- Synthetic study toward vibralactone.Beilstein journal of organic chemistry · 2025Article
- Verbenone prevents cyclophosphamide-induced oxidative stress, inflammation, fibrosis, and cellular changes in the kidneys of Swiss albino mice by targeting NF-ĸB/TGF-β signaling pathways.Iranian journal of basic medical sciences · 2025Article
- Structure and Biosynthesis of Perochalasins A-C, Open-Chain Merocytochalasans Produced by the Marine-Derived FungusJournal of natural products · 2024Article
- Visible-light-mediated synthesis of oxime estersRSC advances · 2023Article
- Secondary Metabolites from Fungi-In Honor of Prof. Dr. Ji-Kai Liu's 60th Birthday.Journal of fungi (Basel, Switzerland) · 2022Article
- [20(22)Journal of fungi (Basel, Switzerland) · 2022Article
- Structure and absolute configuration assignments of ochracines F-L, chamigrane and cadinane sesquiterpenes from the basidiomyceteRSC advances · 2021Article
- Irpexoates A-D, Four Triterpenoids with Malonyl Modifications from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus.Natural products and bioprospecting · 2018Article
- PcxL and HpxL are flavin-dependent, oxime-formingThe Journal of biological chemistry · 2018Article
- Vibralactone Biogenesis-Associated Analogues from Submerged Cultures of the Fungus Boreostereum vibrans.Natural products and bioprospecting · 2018Article
- Natural Products Research in China From 2015 to 2016.Frontiers in chemistry · 2018Review
- Lanostane triterpenoids from fruiting bodies of basidiomycete Stereum sp., structures and biological activities.The Journal of antibiotics · 2017Article
- Synthesis and Biological Activity of Novel (Z)- and (E)-Verbenone Oxime Esters.Molecules (Basel, Switzerland) · 2017Article
- Synthesis and Antifungal Activity of Novel 3-Caren-5-One Oxime Esters.Molecules (Basel, Switzerland) · 2017Article
- Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Chemical reviews · 2017Review
- Synthesis and Cytotoxicity Evaluation of Tropinone Derivatives.Natural products and bioprospecting · 2017Article
- Novel Natural Oximes and Oxime Esters with a Vibralactone Backbone from the Basidiomycete Boreostereum vibrans.ChemistryOpen · 2016Article
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Authors and funding
10 authors.
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Abstract
A variety of novel natural products with significant bioactivities are produced by the basidiomycete Boreostereum vibrans. In the present study, we describe 16 novel natural oximes and oxime esters with a vibralactone backbone, vibralactoximes, which were isolated from the scale-up fermentation broth of B. vibrans. Their structures were determined through extensive spectroscopic analyses. These compounds represent the first oxime esters from nature. The hypothetical biosynthetic pathway of these compounds was also proposed. Seven compounds exhibited significant pancreatic lipase inhibitory activity, while ten compounds exhibited cytotoxicities against five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480), with IC50 values comparable with those of cisplatin.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.