Evidence map›Paper›PMID 27330126›Full record

ReviewDiabetes care2016

Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report.

David M Maahs, Bruce A Buckingham, Jessica R Castle, Ali Cinar, Edward R Damiano, Eyal Dassau, J Hans DeVries, Francis J Doyle, Steven C Griffen, Ahmad Haidar and 14 more

Open access · bronzeAbstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in Diabetes care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 4 pooled it
29.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 4 syntheses or guidelines pooled it, 215 citations in OpenAlex.

  1. Pooled it
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 19 institutions in 7 countries.

David M MaahsBarbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO.
Bruce A BuckinghamDivision of Pediatric Endocrinology and Diabetes, Department of Pediatric Endocrinology, Stanford University, Stanford, CA.
Jessica R CastleDepartment of Medicine, Division of Endocrinology, Harold Schnitzer Diabetes Health Center, Oregon Health & Science University, Portland, OR.
Ali CinarDepartment of Chemical and Biological Engineering, Illinois Institute of Technology, Chicago, IL.
Edward R DamianoDepartment of Biomedical Engineering, Boston University, Boston, MA.
Eyal DassauDepartment of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA.
J Hans DeVriesDepartment of Endocrinology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
Francis J DoyleDepartment of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA.
Steven C GriffenJDRF, New York, NY.
Ahmad HaidarBiomedical Engineering Department, McGill University, Montreal, Quebec, Canada Division of Endocrinology, McGill University, Montreal, Quebec, Canada.
Lutz HeinemannProfil Institute for Metabolic Research, Neuss, Germany.
Roman HovorkaWellcome Trust-Medical Research Clinical Institute of Metabolic Science, University of Cambridge, Cambridge, U.K.
Timothy W JonesTelethon Kids Institute, The University of Western Australia, Perth, Australia.
Craig KollmanJaeb Center for Health Research, Tampa, FL.
Boris KovatchevUniversity of Virginia, Charlottesville, VA.
Brian L LevyJohnson & Johnson Diabetes Care Companies, Wayne, PA.
Revital NimriJesse Z and Sara Lea Shafer Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Sackler Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel.
David N O'NealDepartment of Medicine, University of Melbourne, St. Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia.
Moshe PhilipJesse Z and Sara Lea Shafer Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Sackler Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel.
Eric RenardDepartment of Endocrinology, Diabetes, and Nutrition, Montpellier University Hospital, INSERM Clinical Investigation Centre 1411, Institute of Functional Genomics, CNRS UMR 5203, INSERM U1191, University of Montpellier, Montpellier, France.
Steven J RussellDepartment of Biomedical Engineering, Boston University, Boston, MA Diabetes Unit and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Stuart A WeinzimerYale University School of Medicine, New Haven, CT.
Howard ZisserDepartment of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA.
John W LumJaeb Center for Health Research, Tampa, FL jlum@jaeb.org.
Harvard University · USJaeb Center for Health Research · USSchneider Children's Medical Center · ILBoston University · USBreakthrough T1D · USCentre National de la Recherche Scientifique · FRIllinois Institute of Technology · USJohnson & Johnson (United States) · USMcGill University · CAOregon Health & Science University · USProfil Institute for Metabolic Research · DEStanford University · USThe Kids Research Institute Australia · AUUniversity of Amsterdam · NLUniversity of California, Santa Barbara · USUniversity of Colorado Denver · USUniversity of Melbourne · AUUniversity of Virginia · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Fault-tolerant Control Systems for Artificial PancreasDP3DK101077 · NIDDK · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CINAR, ALI · 2013 to 2013
$2.0M
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS DP3 DK101077
6 · The paper itself

Abstract

Research on and commercial development of the artificial pancreas (AP) continue to progress rapidly, and the AP promises to become a part of clinical care. In this report, members of the JDRF Artificial Pancreas Project Consortium in collaboration with the wider AP community 1) advocate for the use of continuous glucose monitoring glucose metrics as outcome measures in AP trials, in addition to HbA1c, and 2) identify a short set of basic, easily interpreted outcome measures to be reported in AP studies whenever feasible. Consensus on a broader range of measures remains challenging; therefore, reporting of additional metrics is encouraged as appropriate for individual AP studies or study groups. Greater consistency in reporting of basic outcome measures may facilitate the interpretation of study results by investigators, regulatory bodies, health care providers, payers, and patients themselves, thereby accelerating the widespread adoption of AP technology to improve the lives of people with type 1 diabetes.

Indexed as

Pancreas, ArtificialBlood GlucoseClinical Trials as TopicDiabetes Mellitus, Type 1Glycated HemoglobinHumansOutcome Assessment, Health CareBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID27330126
PMCPMC4915553
OpenAlexW2469701129

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.