Evidence map›Paper›PMID 27339750›Full record

ReviewCurrent atherosclerosis reports2016

Imaging Atherosclerotic Plaque Calcification: Translating Biology.

Grant Bailey, Judith Meadows, Alan R Morrison

Open access · greenAbstract readReview
In one paragraph

Review in Current atherosclerosis reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Advances in CT Techniques in Vascular Calcification.Frontiers in cardiovascular medicine · 2021
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Coronary Artery Plaque Imaging.Current atherosclerosis reports · 2017
    Review
  13. Calcification in atherosclerotic lesions.Current opinion in lipidology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Grant BaileyDepartment of Internal Medicine (Section of Cardiovascular Medicine), Yale Cardiovascular Research Center, Yale University School of Medicine, New Haven, CT, 06511, USA.
Judith MeadowsDepartment of Internal Medicine (Section of Cardiovascular Medicine), Yale Cardiovascular Research Center, Yale University School of Medicine, New Haven, CT, 06511, USA.
Alan R MorrisonDepartment of Internal Medicine (Section of Cardiovascular Medicine), Alpert Medical School at Brown University, Providence, RI, 02903, USA. alan_morrison@brown.edu.
Brown University · USVA Connecticut Healthcare System · USYale University · US

Funding

Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI YAO, HONGWEI · 2013 to 2022
$21.3M
Calcific Atherosclerosis is Mediated by Macrophage Adhesion SignalingIK2BX002527 · VA · VA CONNECTICUT HEALTHCARE SYSTEM · PI MORRISON, ALAN ROSS · 2015 to 2017
–
BLRD VA IK2 BX002527NIGMS NIH HHS P20 GM103652
6 · The paper itself

Abstract

Calcification of atherosclerotic lesions was long thought to be an age - related, passive process, but increasingly data has revealed that atherosclerotic calcification is a more active process, involving complex signaling pathways and bone-like genetic programs. Initially, imaging of atherosclerotic calcification was limited to gross assessment of calcium burden, which is associated with total atherosclerotic burden and risk of cardiovascular mortality and of all cause mortality. More recently, sophisticated molecular imaging studies of the various processes involved in calcification have begun to elucidate information about plaque calcium composition and consequent vulnerability to rupture, leading to hard cardiovascular events like myocardial infarction. As such, there has been renewed interest in imaging calcification to advance risk assessment accuracy in an evolving era of precision medicine. Here we summarize recent advances in our understanding of the biologic process of atherosclerotic calcification as well as some of the molecular imaging tools used to assess it.

Indexed as

AnimalsCalcinosisHumansMolecular ImagingPlaque, AtheroscleroticPrecision MedicineAtherosclerosisCalcificationCoronary artery diseaseMolecular imagingSodium fluoride PETVulnerable plaque

Identifiers

PMID27339750
PMCPMC5206894
OpenAlexW2470044894

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.