Evidence map›Paper›PMID 27352117›Full record

ArticleJournal of racial and ethnic health disparities2017

A National Assessment of Medication Adherence to Statins by the Racial Composition of Neighborhoods.

Andrew M Davis, Michael S Taitel, Jenny Jiang, Dima M Qato, Monica E Peek, Chia-Hung Chou, Elbert S Huang

Open access · greenAbstract read
In one paragraph

Article in Journal of racial and ethnic health disparities, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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  15. Depressive Symptoms Are Associated With Low Treatment Adherence in African American Individuals With Systemic Lupus Erythematosus.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Andrew M DavisDivision of General Internal Medicine, University of Chicago, 5841 S. Maryland Ave, MC3051, Chicago, IL, 60637, USA. amd@uchicago.edu.
Michael S TaitelClinical Outcomes and Analytic Services, Walgreen Co, Deerfield, IL, USA.
Jenny JiangClinical Outcomes and Analytic Services, Walgreen Co, Deerfield, IL, USA.
Dima M QatoDepartment of Pharmacy Systems, Outcomes, and Policy, Center for Pharmacoepidemiology and Pharmacoeconomic Research, University of Illinois College of Pharmacy, Chicago, IL, USA.
Monica E PeekDivision of General Internal Medicine, University of Chicago, 5841 S. Maryland Ave, MC3051, Chicago, IL, 60637, USA.
Chia-Hung ChouDivision of General Internal Medicine, University of Chicago, 5841 S. Maryland Ave, MC3051, Chicago, IL, 60637, USA.
Elbert S HuangDivision of General Internal Medicine, University of Chicago, 5841 S. Maryland Ave, MC3051, Chicago, IL, 60637, USA.
University of Chicago · USWalgreens (United States) · USUniversity of Illinois Urbana-Champaign · US

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MILDA Renne SAUNDERS · 2011 to 2026
$10.0M
Research and Mentorship in Medical Decision Making in DiabetesK24DK105340 · NIDDK · UNIVERSITY OF CHICAGO · PI HUANG, ELBERT S. · 2015 to 2019
$884k
NIDDK NIH HHS K24 DK105340NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

Adherence to statins is lower in black and Hispanic patients and is linked to racial/ethnic disparities in cardiovascular mortality. Poverty, education, and prescription coverage differentials are typically invoked to explain adherence disparities, but analyses at the level of neighborhoods and their pharmacies may provide additional insights. Among individuals filling new statin prescriptions in a national pharmacy chain (N = 326,171), we compared adherence for patients residing in mostly minority neighborhoods to those living in mainly white areas. In analyses adjusting for patient-level factors associated with poor adherence, including age, insurance, payer, prescription cost, and convenience, patients residing in black and Hispanic neighborhoods had 2-3 weeks less statin therapy over 1 year, a pattern not seen in Asian areas. In black and Hispanic neighborhoods, good adherence was associated with co-pays under $10, the use of 90-day refills, and payers other than Medicaid. Efforts to improve medication adherence for vulnerable populations may benefit from interventions at the level of local pharmacies, as well as medication benefit redesign.

Indexed as

Drug MonitoringFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedRacial GroupsResidence CharacteristicsRetrospective StudiesUnited StatesHydroxymethylglutaryl-CoA Reductase InhibitorsCardiovascular diseaseMedication adherenceNeighborhoodPharmaciesRacial and ethnic disparitiesStatin therapy

Identifiers

PMID27352117
PMCPMC5195907
OpenAlexW2471381278

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.