Evidence map›Paper›PMID 27366132›Full record

Trial reportJournal of the International Society of Sports Nutrition2016

Effects of thirty and sixty minutes of moderate-intensity aerobic exercise on postprandial lipemia and inflammation in overweight men: a randomized cross-over study.

Sam R Emerson, Stephanie P Kurti, Brian S Snyder, Karthikeyan Sitaraman, Mark D Haub, Sara K Rosenkranz

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Who would benefit most from postprandial lipid screening?Clinical nutrition (Edinburgh, Scotland) · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sam R EmersonPhysical Activity and Nutrition Clinical Research Consortium, Department of Food, Nutrition, Dietetics, & Health, Kansas State University, 212 Justin Hall, 1324 Lovers Lane, Manhattan, KS 66506 USA.
Stephanie P KurtiDepartment of Kinesiology, 1A Natatorium, Kansas State University, Manhattan, KS 66506 USA.
Brian S SnyderPhysical Activity and Nutrition Clinical Research Consortium, Department of Food, Nutrition, Dietetics, & Health, Kansas State University, 212 Justin Hall, 1324 Lovers Lane, Manhattan, KS 66506 USA.
Karthikeyan SitaramanPhysical Activity and Nutrition Clinical Research Consortium, Department of Food, Nutrition, Dietetics, & Health, Kansas State University, 212 Justin Hall, 1324 Lovers Lane, Manhattan, KS 66506 USA.
Mark D HaubPhysical Activity and Nutrition Clinical Research Consortium, Department of Food, Nutrition, Dietetics, & Health, Kansas State University, 212 Justin Hall, 1324 Lovers Lane, Manhattan, KS 66506 USA.
Sara K RosenkranzPhysical Activity and Nutrition Clinical Research Consortium, Department of Food, Nutrition, Dietetics, & Health, Kansas State University, 212 Justin Hall, 1324 Lovers Lane, Manhattan, KS 66506 USA.
Clinical Research Consortium · USKansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe transient rise in blood lipids following a high-fat meal (HFM), known as postprandial lipemia, is linked to systemic inflammation and cardiovascular disease, but can be blunted by exercise. However, minimal research has investigated the effects of realistic exercise bouts on postprandial lipemia and inflammation in at-risk individuals. The purpose of this study was to assess the effects of moderate-intensity aerobic exercise lasting 30 or 60 min performed the evening before a HFM, on postprandial lipemia and inflammation in overweight, insufficiently active men.

methodsIn this randomized-crossover study, twelve participants remained sedentary (CON), or performed a brisk walk on a treadmill at 60 % VO2peak for either 30 min (EX-30) or 60 min (EX-60), after which they consumed a small snack (270 kcal) to partially replace exercise energy expenditure. Following a 12-h overnight fast, participants consumed a standard HFM (1 g fat/kg; 1 g CHO/kg; 1117.8 ± 117.0 kcal). Blood draws were performed at baseline (pre-HFM) and 1, 2, 4, 6, and 8 h post-HFM to assess glucose, insulin, lipids, and systemic inflammation.

resultsThere were no significant differences (p > 0.05) in fasting triglycerides between EX-60 (118.7 ± 68.3 mg/dL), CON (134.8 ± 66.2 mg/dL) or EX-30 (135.5 ± 85.4 mg/dL). There were no differences in peak, time-to-peak, total or incremental area-under-the-curve between trials for triglyceride response (p > 0.05). There was no significant main effect of time (p > 0.05) in IL-1ra, IL-4, IL-5, IL-6, IL-10 or TNF-α from baseline to 8 h post-HFM in any trial.

conclusionsIn summary, we found that in overweight, insufficiently active men, neither 30 nor 60 min of moderate-intensity exercise performed 12 h prior to a HFM attenuated postprandial lipemia or inflammation, which could potentially be explained by the partial caloric replacement of exercise energy expenditure.

Indexed as

Diet, High-FatPostprandial PeriodAdultBlood GlucoseCross-Over StudiesCytokinesEnergy IntakeEnergy MetabolismExerciseHumansHyperlipidemiasInflammationInsulinLipidsMaleOverweightBlood GlucoseCytokinesInsulinLipidsTriglyceridesCytokinesHigh fat mealTriglycerides

Identifiers

PMID27366132
PMCPMC4928275
OpenAlexW2464586806

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.