Evidence map›Paper›PMID 27376089›Full record

ReviewJournal of diabetes research2016

The Role of Hyperglycemia and Insulin Resistance in the Development and Progression of Pulmonary Arterial Hypertension.

Daniel Grinnan, Grant Farr, Adam Fox, Lori Sweeney

Open access · goldAbstract readReview
In one paragraph

Review in Journal of diabetes research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Manipulation of Post-Prandial Hyperglycaemia in Type 2 Diabetes: An Update for Practitioners.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  6. Review
  7. Insulin Resistance Is Associated with Right Ventricular Dysfunction.Annals of the American Thoracic Society · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. American journal of physiology. Lung cellular and molecular physiology · 2020
    Article
  15. Article
  16. The burden of comorbidities in pulmonary arterial hypertension.European heart journal supplements : journal of the European Society of Cardiology · 2019
    Article
  17. Review
  18. Diabetic lung disease: fact or fiction?Reviews in endocrine & metabolic disorders · 2019
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Daniel GrinnanDivision of Pulmonary and Critical Care Medicine, Virginia Commonwealth University Health System, Richmond, VA 23298, USA.
Grant FarrDivision of Pulmonary and Critical Care Medicine, Virginia Commonwealth University Health System, Richmond, VA 23298, USA.
Adam FoxDepartment of Internal Medicine, Virginia Commonwealth University Health System, Richmond, VA 23298, USA.
Lori SweeneyDivision of Endocrinology, Virginia Commonwealth University Health System, Richmond, VA 23298, USA.
Virginia Commonwealth University · USUniversity Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension is a progressive disorder which often leads to right ventricular failure and death. While the existing classification system for pulmonary hypertension does not account for the impact of diabetes mellitus, evidence is emerging that suggests that diabetes is associated with pulmonary hypertension and that diabetes modifies the course of pulmonary hypertension. There is also growing radiographic, hemodynamic, biochemical, and pathologic data supporting an association between diabetes and pulmonary hypertension. More robust epidemiologic studies are needed to confirm an association between diabetes and pulmonary hypertension and to show that diabetes is a disease modifier in pulmonary hypertension. In addition, evaluating the effects of glucose control in animals with pulmonary hypertension and diabetes (as well as in humans) is warranted.

Indexed as

Insulin ResistanceDiabetes MellitusDisease ProgressionGlucose IntoleranceHumansHyperglycemiaHypertension, PulmonaryMicrovesselsPulmonary CirculationVentricular Dysfunction, Right

Identifiers

PMID27376089
PMCPMC4916286
OpenAlexW2413545254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.