Evidence map›Paper›PMID 27378227›Full record

ArticleMolecules and cells2016

A Pair of Oviduct-Born Pickpocket Neurons Important for Egg-Laying in Drosophila melanogaster.

Hyunjin Lee, Hyun Woo Choi, Chen Zhang, Zee-Yong Park, Young-Joon Kim

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Time series transcriptome analysis implicates the circadian clock in theProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  3. Regulation ofiScience · 2022
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyunjin LeeSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.
Hyun Woo ChoiSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.
Chen ZhangSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.
Zee-Yong ParkSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.
Young-Joon KimSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.
Gwangju Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During copulation, male Drosophila transfers Sex Peptide (SP) to females where it acts on internal sensory neurons expressing pickpocket (ppk). These neurons induce a post-mating response (PMR) that includes elevated egg-laying and refractoriness to re-mating. Exactly how ppk neurons regulate the different aspects of the PMR, however, remains unclear. Here, we identify a small subset of the ppk neurons which requires expression of a pre-mRNA splicing factor CG3542 for egg-laying, but not refractoriness to mating. We identify two CG3542-ppk expressing neurons that innervate the upper oviduct and appear to be responsible for normal egg-laying. Our results suggest specific subsets of the ppk neurons are responsible for each PMR component.

Indexed as

OvipositionAnimalsCell LineDrosophila melanogasterDrosophila ProteinsFemaleGene Expression RegulationMalePeptidesPhosphorylationProteomicsSensory Receptor CellsSexual Behavior, AnimalSodium ChannelsCG3542 protein, DrosophilaDrosophila ProteinsPeptidesSodium ChannelsCG3542egg-layingphosphoproteinpickpocketpost mating responsesex peptide

Identifiers

PMID27378227
PMCPMC4959023
OpenAlexW2499235519

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.