ArticleOncotarget2016
Abnormal organization of white matter networks in patients with subjective cognitive decline and mild cognitive impairment.
Article in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brain network disintegration as a final common pathway for delirium: a systematic review and qualitative meta-analysis.NeuroImage. Clinical · 2019Pooled it
- Quantitative susceptibility mapping for Alzheimer's disease, mild cognitive impairment, and normal aging: evaluation of corpus callosum.Quantitative imaging in medicine and surgery · 2025Article
- The brain network hub degeneration in Alzheimer's disease.Biophysics reports · 2024Article
- Review
- Hippocampal connectivity and memory decline in cognitively intact APOE ε4 carriers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Review
- Sex differences in the structural rich-club connectivity in patients with Alzheimer's disease.Frontiers in aging neuroscience · 2023Article
- Optimized Multiscale Entropy Model Based on Resting-State fMRI for Appraising Cognitive Performance in Healthy Elderly.Computational and mathematical methods in medicine · 2022Article
- Exploring Network Properties Across Preclinical Stages of Alzheimer's Disease Using a Visual Short-Term Memory and Attention Task with High-Density Electroencephalography: A Brain-Connectome Neurophysiological Study.Journal of Alzheimer's disease : JAD · 2022Article
- The interplay between gray matter and white matter neurodegeneration in subjective cognitive decline.Aging · 2021Article
- Progressive Brain Degeneration From Subjective Cognitive Decline to Amnestic Mild Cognitive Impairment: Evidence From Large-Scale Anatomical Connection Classification Analysis.Frontiers in aging neuroscience · 2021Article
- Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease.Molecular neurodegeneration · 2020Review
- Alterations of white matter integrity associated with cognitive deficits in patients with glioma.Brain and behavior · 2020Article
- A Novel Connectome-Based Electrophysiological Study of Subjective Cognitive Decline Related to Alzheimer's Disease by Using Resting-State High-Density EEG EGI GES 300.Brain sciences · 2020Article
- Subjective Cognitive Decline and Related Cognitive Deficits.Frontiers in neurology · 2020Review
- Altered Rich-Club Organization and Regional Topology Are Associated With Cognitive Decline in Patients With Frontal and Temporal Gliomas.Frontiers in human neuroscience · 2020Article
- Abnormal Rich Club Organization of Structural Network as a Neuroimaging Feature in Relation With the Severity of Primary Insomnia.Frontiers in psychiatry · 2020Article
- Diffusion tensor imaging reveals abnormal brain networks in elderly subjects with subjective cognitive deficits.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Article
- Low carotid wall shear stress independently accelerates the progression of cognitive impairment and white matter lesions in the elderly.Oncotarget · 2018Article
- MRI Asymmetry Index of Hippocampal Subfields Increases Through the Continuum From the Mild Cognitive Impairment to the Alzheimer's Disease.Frontiers in neuroscience · 2018Article
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Network analysis has been widely used in studying Alzheimer's disease (AD). However, how the white matter network changes in cognitive impaired patients with subjective cognitive decline (SCD) (a symptom emerging during early stage of AD) and amnestic mild cognitive impairment (aMCI) (a pre-dementia stage of AD) is still unclear. Here, structural networks were constructed respectively based on FA and FN for 36 normal controls, 21 SCD patients, and 33 aMCI patients by diffusion tensor imaging and graph theory. Significantly lower efficiency was found in aMCI patients than normal controls (NC). Though not significant, the values in those with SCD were intermediate between aMCI and NC. In addition, our results showed significantly altered betweenness centrality located in right precuneus, calcarine, putamen, and left anterior cingulate in aMCI patients. Furthermore, association was found between network metrics and cognitive impairment. Our study suggests that the structural network properties might be preserved in SCD stage and disrupted in aMCI stage, which may provide novel insights into pathological mechanisms of AD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.