ReviewFrontiers in aging neuroscience2016
Influence of Aerobic Training and Combinations of Interventions on Cognition and Neuroplasticity after Stroke.
Review in Frontiers in aging neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of different exercise interventions on motor function in patients at different post-stroke recovery phases: a systematic review and Bayesian network meta-analysis.Frontiers in neurology · 2025Pooled it
- Aerobic exercises and cognitive function in post-stroke patients: A systematic review with meta-analysis.Medicine · 2022Pooled it
- Effect of Physical Activity on Cognitive Impairment in Patients With Cerebrovascular Diseases: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2022Pooled it
- Cognitive and Linguistic Benefits of Aerobic Exercise: A State-of-the-Art Systematic Review of the Stroke Literature.Frontiers in rehabilitation sciences · 2021Pooled it
- Home-Based Multimodal Exergame Prototype for Patients With Chronic Stroke: Cross-Sectional Content Validation and Prospective Single-Arm Feasibility Study.JMIR serious games · 2026Article
- Harnessing Neuroplasticity: The Role of Priming in Enhancing Post Stroke Motor Function.Restorative neurology and neuroscience · 2026Review
- Distinct neural mechanisms underlying the effects of agility and resistance-aerobic training on executive function and gait in young adults.Frontiers in psychology · 2026Article
- Evaluation of the functional outcome and mobility of patients after stroke depending on their cognitive state.Scientific reports · 2024Article
- Developmental outcomes with perinatal exposure (DOPE) to prescription opioids.NeuroImmune pharmacology and therapeutics · 2023Review
- Enhanced Gait Recovery in Chronic Post-COVID-19 Stroke: The Role of Combined Physical Rehabilitation.Reports (MDPI) · 2023Article
- Article
- Brain Health Indicators Following Acute Neuro-Exergaming: Biomarker and Cognition in Mild Cognitive Impairment (MCI) after Pedal-n-Play (iPACES).Brain sciences · 2023Article
- Aerobic exercise as a promising nonpharmacological therapy for the treatment of substance use disorders.Journal of neuroscience research · 2022Review
- The Effect of Endurance Training on Serum BDNF Levels in the Chronic Post-Stroke Phase: Current Evidence and Qualitative Systematic Review.Journal of clinical medicine · 2022Review
- Effects of Combined Interventions with Aerobic Physical Exercise and Cognitive Training on Cognitive Function in Stroke Patients: A Systematic Review.Brain sciences · 2021Review
- Is High-Intensity Interval Training Suitable to Promote Neuroplasticity and Cognitive Functions after Stroke?International journal of molecular sciences · 2021Review
- The Enhanced Interactive Physical and Cognitive Exercise System (iPACESJournal of clinical medicine · 2018Article
- Targeting phosphodiesterase 4 as a potential therapeutic strategy for enhancing neuroplasticity following ischemic stroke.International journal of biological sciences · 2018Review
- Exercise Training Increases Parietal Lobe Cerebral Blood Flow in Chronic Stroke: An Observational Study.Frontiers in aging neuroscience · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stroke often aggravated age-related cognitive impairments that strongly affect several aspects of quality of life. However, few studies are, to date, focused on rehabilitation strategies that could improve cognition. Among possible interventions, aerobic training is well known to enhance cardiovascular and motor functions but may also induce beneficial effects on cognitive functions. To assess the effectiveness of aerobic training on cognition, it seems necessary to know whether training promotes the neuroplasticity in brain areas involved in cognitive functions. In the present review, we first explore in both human and animal how aerobic training could improve cognition after stroke by highlighting the neuroplasticity mechanisms. Then, we address the potential effect of combinations between aerobic training with other interventions, including resistance exercises and pharmacological treatments. In addition, we postulate that classic recommendations for aerobic training need to be reconsidered to target both cognition and motor recovery because the current guidelines are only focused on cardiovascular and motor recovery. Finally, methodological limitations of training programs and cognitive function assessment are also developed in this review to clarify their effectiveness in stroke patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.