ArticleJournal of applied physiology (Bethesda, Md. : 1985)1989
Venous occlusion plethysmography reduces arterial diameter and flow velocity.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01881828 (A Randomized Trial of Metformin as Adjunct Therapy for Overweight Adolescents With Type 1 Diabetes), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial of Metformin as Adjunct Therapy for Overweight Adolescents With Type 1 Diabetes
Who cites it
15 citing papers in PubMed, 60 citations in OpenAlex.
- Near-infrared diffuse correlation spectroscopy tracks changes in oxygen delivery and utilization during exercise with and without isolated arterial compression.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Trial
- Venous occlusion plethysmography versus Doppler ultrasound in the assessment of leg blood flow during calf exercise.European journal of applied physiology · 2011Trial
- Human calf precapillary resistance decreases in response to small cumulative increases in venous congestion pressure.The Journal of physiology · 1998Trial
- Article
- Effect of Lower Limb Venous Dilation on the Autonomic Cardiac Response among Healthy Young Men.Healthcare (Basel, Switzerland) · 2023Article
- Single-leg exercise training augments in vivo skeletal muscle oxidative flux and vascular content and function in adults with type 2 diabetes.The Journal of physiology · 2022Article
- Review of early development of near-infrared spectroscopy and recent advancement of studies on muscle oxygenation and oxidative metabolism.The journal of physiological sciences : JPS · 2019Review
- Cuff inflation time significantly affects blood flow recorded with venous occlusion plethysmography.European journal of applied physiology · 2019Article
- Venous occlusion plethysmography vs. Doppler ultrasound in the assessment of leg blood flow kinetics during different intensities of calf exercise.European journal of applied physiology · 2018Article
- Acute vitamin C improves cardiac function, not exercise capacity, in adults with type 2 diabetes.Diabetology & metabolic syndrome · 2018Article
- Hybrid diffuse optical techniques for continuous hemodynamic measurement in gastrocnemius during plantar flexion exercise.Journal of biomedical optics · 2015Article
- Sex differences in the effects of type 2 diabetes on exercise performance.Medicine and science in sports and exercise · 2015Article
- Transit delay and flow quantification in muscle with continuous arterial spin labeling perfusion-MRI.Journal of magnetic resonance imaging : JMRI · 2008Article
- Muscle metabolism with blood flow restriction in chronic fatigue syndrome.Journal of applied physiology (Bethesda, Md. : 1985) · 2004Article
- Blood flow and oxygenation in peritendinous tissue and calf muscle during dynamic exercise in humans.The Journal of physiology · 2000Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The measurement of peripheral blood flow by plethysmography assumes that the cuff pressure required for venous occlusion does not decrease arterial inflow. However, studies in five normal subjects suggested that calf blood flow measured with a plethysmograph was less than arterial inflow calculated from Doppler velocity measurements. We hypothesized that the pressure required for venous occlusion may have decreased arterial velocity. Further studies revealed that systolic diameter of the superficial femoral artery under a thigh cuff decreased from 7.7 +/- 0.4 to 5.6 +/- 0.7 mm (P less than 0.05) when the inflation pressure was increased from 0 to 40 mmHg. Cuff inflation to 40 mmHg also reduced mean velocity 38% in the common femoral artery and 47% in the popliteal artery. Inflation of a cuff on the arm reduced mean velocity in the radial artery 22% at 20 mmHg, 26% at 40 mmHg, and 33% at 60 mmHg. We conclude that inflation of a cuff on an extremity to low pressures for venous occlusion also caused a reduction in arterial diameter and flow velocity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.