ArticleScientific reports2016
DisSim: an online system for exploring significant similar diseases and exhibiting potential therapeutic drugs.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Article
- Computational Methods for Identifying Similar Diseases.Molecular therapy. Nucleic acids · 2019Review
- ProbPFP: a multiple sequence alignment algorithm combining hidden Markov model optimized by particle swarm optimization with partition function.BMC bioinformatics · 2019Article
- Construction of Disease Similarity Networks Using Concept Embedding and Ontology.Studies in health technology and informatics · 2019Article
- Predicting disease-related phenotypes using an integrated phenotype similarity measurement based on HPO.BMC systems biology · 2019Article
- GBDTCDA: Predicting circRNA-disease Associations Based on Gradient Boosting Decision Tree with Multiple Biological Data Fusion.International journal of biological sciences · 2019Article
- PWCDA: Path Weighted Method for Predicting circRNA-Disease Associations.International journal of molecular sciences · 2018Article
- Article
- Identifying diseases-related metabolites using random walk.BMC bioinformatics · 2018Article
- BCDForest: a boosting cascade deep forest model towards the classification of cancer subtypes based on gene expression data.BMC bioinformatics · 2018Article
- Effective norm emergence in cell systems under limited communication.BMC bioinformatics · 2018Article
- Higher-order partial least squares for predicting gene expression levels from chromatin states.BMC bioinformatics · 2018Article
- Automatic infection detection based on electronic medical records.BMC bioinformatics · 2018Article
- A framework for analyzing DNA methylation data from Illumina Infinium HumanMethylation450 BeadChip.BMC bioinformatics · 2018Article
- Measuring phenotype-phenotype similarity through the interactome.BMC bioinformatics · 2018Article
- Disease Ontology: improving and unifying disease annotations across species.Disease models & mechanisms · 2018Article
- Prediction of Alzheimer's Disease-Associated Genes by Integration of GWAS Summary Data and Expression Data.Frontiers in genetics · 2018Article
- Relationship Between Alzheimer's Disease and the Immune System: A Meta-Analysis of Differentially Expressed Genes.Frontiers in neuroscience · 2018Article
- EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs.Current gene therapy · 2018Article
- A Novel Protein Subcellular Localization Method With CNN-XGBoost Model for Alzheimer's Disease.Frontiers in genetics · 2018Article
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9 authors.
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Abstract
The similarity of pair-wise diseases reveals the molecular relationships between them. For example, similar diseases have the potential to be treated by common therapeutic chemicals (TCs). In this paper, we introduced DisSim, an online system for exploring similar diseases, and comparing corresponding TCs. Currently, DisSim implemented five state-of-the-art methods to measure the similarity between Disease Ontology (DO) terms and provide the significance of the similarity score. Furthermore, DisSim integrated TCs of diseases from the Comparative Toxicogenomics Database (CTD), which can help to identify potential relationships between TCs and similar diseases. The system can be accessed from http://123.59.132.21:8080/DisSim.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.