GuidelinePediatrics2016
Updated Clinical Guidelines for Diagnosing Fetal Alcohol Spectrum Disorders.
Guideline in Pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07456579 (Assessment of Alcohol and Cannabis Use Among Pregnant Women in Slovenia and Meconium Microbiome Analysis of Positive Samples), which is not on this map. Cited by 409 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Alcohol and Cannabis Use Among Pregnant Women in Slovenia and Meconium Microbiome Analysis of Positive Samples
Who cites it
409 citing papers in PubMed, 2 syntheses or guidelines pooled it, 855 citations in OpenAlex.
- Prenatal alcohol exposure and associations with physical size, dysmorphology and neurodevelopment: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Recent breakthroughs in understanding the cerebellum's role in fetal alcohol spectrum disorder: A systematic review.Alcohol (Fayetteville, N.Y.) · 2024Pooled it
- Families Moving Forward Connect mHealth Intervention for Caregivers of Children With Fetal Alcohol Spectrum Disorders: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Results of a pilot randomized controlled trial of Tuning in to Kids for children with FASD in nonbiological parent care.Alcohol, clinical & experimental research · 2025Trial
- Choline enhances elicited imitation memory performance in preschool children with prenatal alcohol exposure: a cumulative report of 3 randomized controlled trials.The American journal of clinical nutrition · 2025Trial
- Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes.Journal of neurodevelopmental disorders · 2022Trial
- Third trimester-equivalent alcohol exposure reduces neurons in males and increases Vglut2Neuropharmacology · 2026Article
- Prenatal Alcohol Exposure as a Potential Contributor to Hydranencephaly: Clinical and Neurodevelopmental Perspectives.Clinical case reports · 2026Article
- Quantitative Three-Dimensional Characterization of Facial Dysmorphism in Self-Identified African-American Individuals With Prenatal Alcohol Exposure.Alcohol, clinical & experimental research · 2026Article
- Analysis of fetal MRI data reveals no effect on liver maturation following prenatal alcohol exposure.European radiology · 2026Article
- Increasing Access to FASD-Informed Care: Bringing an Adapted Intervention to Mental Health Providers.Evidence-based practice in child and adolescent mental health · 2026Article
- Alcohol Metabolism into Acetaldehyde in Developing Cerebral Arteries.International journal of molecular sciences · 2026Article
- Meeting the Needs of Neurodivergent Teens for Dialectical Behaviour Therapy: Challenges and Adaptation Strategies From Clinicians, Teens With Fetal Alcohol Spectrum Disorders and Caregivers.Journal of applied research in intellectual disabilities : JARID · 2026Article
- Prenatal Alcohol Exposure and Dysmorphic Features in Adults at Midlife.Alcohol, clinical & experimental research · 2026Article
- Stunting, underweight and thinness in internationally adopted children: prevalence and associated factors in a large cohort study.European journal of pediatrics · 2026Article
- Developmental Neurotoxicity of Alcohol from Neuronal Basis to Behavioural Outcomes: A Comprehensive Review.Neurology international · 2026Review
- Cardiovascular and Cardiometabolic Outcomes in Adults with Fetal Alcohol Spectrum Disorders: A Retrospective Cohort Study.medRxiv : the preprint server for health sciences · 2026Article
- From teratogens to trajectories: Integrating teratology and Developmental Origins of Health and Disease (DOHaD) frameworks for a new take on fetal alcohol spectrum disorders (FASD).Neurobiology of stress · 2026Article
- Validation of the ND-PAE Diagnosis in Children with Heavy Prenatal Alcohol Exposure.Child psychiatry and human development · 2026Article
- Does a Biochemical Approach Facilitate the Diagnosis of Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder in Neonatal Period?International journal of molecular sciences · 2026Review
349 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 17 institutions in 2 countries.
Funding
Abstract
The adverse effects of prenatal alcohol exposure constitute a continuum of disabilities (fetal alcohol spectrum disorders [FASD]). In 1996, the Institute of Medicine established diagnostic categories delineating the spectrum but not specifying clinical criteria by which diagnoses could be assigned. In 2005, the authors published practical guidelines operationalizing the Institute of Medicine categories, allowing for standardization of FASD diagnoses in clinical settings. The purpose of the current report is to present updated diagnostic guidelines based on a thorough review of the literature and the authors' combined expertise based on the evaluation of >10 000 children for potential FASD in clinical settings and in epidemiologic studies in conjunction with National Institute on Alcohol Abuse and Alcoholism-funded studies, the Collaborative Initiative on Fetal Alcohol Spectrum Disorders, and the Collaboration on FASD Prevalence. The guidelines were formulated through conference calls and meetings held at National Institute on Alcohol Abuse and Alcoholism offices in Rockville, MD. Specific areas addressed include the following: precise definition of documented prenatal alcohol exposure; neurobehavioral criteria for diagnosis of fetal alcohol syndrome, partial fetal alcohol syndrome, and alcohol-related neurodevelopmental disorder; revised diagnostic criteria for alcohol-related birth defects; an updated comprehensive research dysmorphology scoring system; and a new lip/philtrum guide for the white population, incorporating a 45-degree view. The guidelines reflect consensus among a large and experienced cadre of FASD investigators in the fields of dysmorphology, epidemiology, neurology, psychology, developmental/behavioral pediatrics, and educational diagnostics. Their improved clarity and specificity will guide clinicians in accurate diagnosis of infants and children prenatally exposed to alcohol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.