Evidence map›Paper›PMID 27494710›Full record

ArticleFly2017

The translation factors of Drosophila melanogaster.

Steven J Marygold, Helen Attrill, Paul Lasko

Open access · hybridAbstract read
In one paragraph

Article in Fly, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Translation in Mitochondrial Ribosomes.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  9. Review
  10. Article
  11. Unconventional translation initiation factor EIF2A is required for Drosophila spermatogenesis.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Steven J Marygolda FlyBase, Department of Physiology , Development and Neuroscience, University of Cambridge , Cambridge , UK.
Helen Attrilla FlyBase, Department of Physiology , Development and Neuroscience, University of Cambridge , Cambridge , UK.
Paul Laskob Department of Biology , McGill University , Bellini Life Sciences Complex, Montreal, Quebec , Canada.
University of Cambridge · GBMcGill University · CA

Funding

Resource Project CoreU41HG000739 · NHGRI · HARVARD UNIVERSITY · PI PERRIMON, NORBERT · 2014 to 2022
$32.3M
CIHR IOP-107945CIHR MOP-44050Medical Research Council G1000968NHGRI NIH HHS U41 HG000739
6 · The paper itself

Abstract

Synthesis of polypeptides from mRNA (translation) is a fundamental cellular process that is coordinated and catalyzed by a set of canonical 'translation factors'. Surprisingly, the translation factors of Drosophila melanogaster have not yet been systematically identified, leading to inconsistencies in their nomenclature and shortcomings in functional (Gene Ontology, GO) annotations. Here, we describe the complete set of translation factors in D. melanogaster, applying nomenclature already in widespread use in other species, and revising their functional annotation. The collection comprises 43 initiation factors, 12 elongation factors, 3 release factors and 6 recycling factors, totaling 64 of which 55 are cytoplasmic and 9 are mitochondrial. We also provide an overview of notable findings and particular insights derived from Drosophila about these factors. This catalog, together with the incorporation of the improved nomenclature and GO annotation into FlyBase, will greatly facilitate access to information about the functional roles of these important proteins.

Indexed as

Protein BiosynthesisAnimalsDrosophila melanogasterDrosophila ProteinsEukaryotic Initiation FactorsMitochondrial ProteinsPeptide Elongation FactorsRibosomal ProteinsDrosophila ProteinsEukaryotic Initiation FactorsMitochondrial ProteinsPeptide Elongation FactorsRibosomal ProteinsDrosophila melanogastertranslation elongation factortranslation initiation factortranslation recycling factortranslation release factortranslation termination factor

Identifiers

PMID27494710
PMCPMC5354226
OpenAlexW2499858706

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.