Evidence map›Paper›PMID 27544781›Full record

ReviewMolecular and cellular endocrinology2017

Mathematical modeling of gonadotropin-releasing hormone signaling.

Amitesh Pratap, Kathryn L Garner, Margaritis Voliotis, Krasimira Tsaneva-Atanasova, Craig A McArdle

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular and cellular endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Modelling KNDy neurons and gonadotropin-releasing hormone pulse generation.Current opinion in endocrine and metabolic research · 2022
    Review
  3. Mathematical models in GnRH research.Journal of neuroendocrinology · 2022
    Review
  4. Article
  5. The Origin of GnRH Pulse Generation: An Integrative Mathematical-Experimental Approach.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  6. Article
  7. Mathematical Modelling of Endocrine Systems.Trends in endocrinology and metabolism: TEM · 2019
    Review
  8. GnRH-A Key Regulator of FSH.Endocrinology · 2019
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amitesh PratapLaboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Whitson Street, Bristol, BS1 3NY, UK.
Kathryn L GarnerLaboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Whitson Street, Bristol, BS1 3NY, UK.
Margaritis VoliotisEPSRC Centre for Predictive Modeling in Healthcare, University of Exeter, Exeter, EX4 4QF, UK.
Krasimira Tsaneva-AtanasovaDepartment of Mathematics, College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, EX4 4QF, UK; EPSRC Centre for Predictive Modeling in Healthcare, University of Exeter, Exeter, EX4 4QF, UK.
Craig A McArdleLaboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Whitson Street, Bristol, BS1 3NY, UK. Electronic address: craig.mcardle@bristol.ac.uk.
University of Bristol · GBEngineering and Physical Sciences Research Council · GB

Funding

Biotechnology and Biological Sciences Research Council J014699Medical Research Council 93447Medical Research Council MR/K021826/1
6 · The paper itself

Abstract

Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes to control reproduction. These are G

Indexed as

Models, BiologicalSignal TransductionAnimalsComputer SimulationGonadotropin-Releasing HormoneHumansInformation TheoryGonadotropin-Releasing HormoneERKGnRHGPCRMathematical modelingMutual informationNFAT

Identifiers

PMID27544781
PMCPMC5446263
OpenAlexW2509503109

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.