Evidence map›Paper›PMID 27602985›Full record

ReviewPharmacological research2016

Homocysteine and hydrogen sulfide in epigenetic, metabolic and microbiota related renovascular hypertension.

Gregory J Weber, Sathnur Pushpakumar, Suresh C Tyagi, Utpal Sen

Open access · greenAbstract readReview
In one paragraph

Review in Pharmacological research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Editorial: Obesity across the life course.Frontiers in public health · 2025
    Article
  7. Article
  8. Review
  9. The interplay of hydrogen sulfide and microRNAs in cardiovascular diseases: insights and future perspectives.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Review
  10. Article
  11. Article
  12. Gut microbiota: a potential new regulator of hypertension.Frontiers in cardiovascular medicine · 2024
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Potential Effects of Natural HBiomolecules · 2022
    Review
  20. Journal of immunology research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gregory J WeberDepartment of Physiology, University of Louisville, School of Medicine, Louisville, KY 40202, United States.
Sathnur PushpakumarDepartment of Physiology, University of Louisville, School of Medicine, Louisville, KY 40202, United States.
Suresh C TyagiDepartment of Physiology, University of Louisville, School of Medicine, Louisville, KY 40202, United States.
Utpal SenDepartment of Physiology, University of Louisville, School of Medicine, Louisville, KY 40202, United States. Electronic address: u0sen001@louisville.edu.
University of Louisville · US

Funding

Hydrogen sulfide mechanism of renal hypertensionR01DK104653 · NIDDK · UNIVERSITY OF LOUISVILLE · PI SEN, UTPAL, TYAGI, SURESH C. · 2015 to 2018
$2.5M
Homocysteine & Angiotensin II in Renovascular RemodelingR01HL104103 · NHLBI · UNIVERSITY OF LOUISVILLE · PI SEN, UTPAL · 2011 to 2015
$1.8M
NHLBI NIH HHS R01 HL104103NIDDK NIH HHS R01 DK104653
6 · The paper itself

Abstract

Over the past several years, hydrogen sulfide (H

Indexed as

AnimalsEpigenesis, GeneticHomocysteineHumansHydrogen SulfideHypertension, RenovascularMetabolomeMicrobiotaHomocysteineHydrogen SulfideEpigeneticsExtracellular matrixFolic acidHomocysteineInflammationMicrobiotamiRNAMMPsPolysulfidesTIMPs

Identifiers

PMID27602985
PMCPMC5107119
OpenAlexW2516330329

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.