Evidence map›Paper›PMID 27628292›Full record

ArticleNeurochemical research2017

Astroglial Vesicular Trafficking in Neurodegenerative Diseases.

Robert Zorec, Vladimir Parpura, Alexei Verkhratsky

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Expression Pattern of theThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 4 countries.

Robert ZorecCelica Biomedical, 1000, Ljubljana, Slovenia. robert.zorec@mf.uni-lj.si.
Vladimir ParpuraAtomic Force Microscopy and Nanotechnology Laboratories, Department of Neurobiology, Civitan International Research Center and Center for Glial Biology in Medicine, Evelyn F. McKnight Brain Institute, University of Alabama, 1719 6th Avenue South, CIRC 429, Birmingham, AL, 35294-0021, USA.
Alexei VerkhratskyFaculty of Life Sciences, The University of Manchester, Manchester, M13 9PT, UK. Alexej.Verkhratsky@manchester.ac.uk.
Celica (Slovenia) · SIUniversity of Alabama · USUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neocortex represents one of the largest estates of the human brain. This structure comprises ~30-40 billions of neurones and even more of non-neuronal cells. Astrocytes, highly heterogeneous homoeostatic glial cells, are fundamental for housekeeping of the brain and contribute to information processing in neuronal networks. Gray matter astrocytes tightly enwrap synapses, contact blood vessels and, naturally, are also in contact with the extracellular space, where convection of fluid takes place. Thus astrocytes receive signals from several distinct extracellular domains and can get excited by numerous mechanisms, which regulate cytosolic concentration of second messengers, such as Ca

Indexed as

Alzheimer DiseaseAnimalsAstrocytesExocytosisHumansNeocortexNeurodegenerative DiseasesNeuronsSecretory VesiclesSNARE ProteinsSynaptic VesiclesSNARE ProteinscAMPCytosolic Ca2+Gliocrine systemGliosignalling moleculesRegulated exocytosisSignallingVesicle dynamics

Identifiers

PMID27628292
OpenAlexW2519946212

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.