Evidence map›Paper›PMID 27645613›Full record

ReviewReviews in endocrine & metabolic disorders2017

Low serum vitamin D-status, air pollution and obesity: A dangerous liaison.

Luigi Barrea, Silvia Savastano, Carolina Di Somma, Maria Cristina Savanelli, Francesca Nappi, Lidia Albanese, Francesco Orio, Annamaria Colao

Open access · hybridAbstract readReview
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.

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  11. Fracture nonunion and delayed union.Journal of the Pediatric Orthopaedic Society of North America · 2024
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  19. Long-term exposure to air pollution increases hip fracture incidence rate and related mortality: analysis of National Hip Fracture Database.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Luigi BarreaI. O.S. & COLEMAN Srl, 80011 Acerra, Naples, Italy. luigi.barrea@unina.it.ORCID 0000-0001-9054-456X
Silvia SavastanoDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131, Naples, Italy.
Carolina Di SommaIRCCS SDN, Napoli Via Gianturco 113, 80143, Naples, Italy.
Maria Cristina SavanelliI. O.S. & COLEMAN Srl, 80011 Acerra, Naples, Italy.
Francesca NappiI. O.S. & COLEMAN Srl, 80011 Acerra, Naples, Italy.
Lidia AlbaneseDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131, Naples, Italy.
Francesco OrioDepartment of Sports Science and Wellness, "Parthenope" University of Naples, Naples, Italy.
Annamaria ColaoDipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131, Naples, Italy.
Federico II University Hospital · ITLuigi Einaudi Foundation · ITParthenope University of Naples · ITSDN Istituto di Ricerca Diagnostica e Nucleare · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this review is to provide a general overview of the possible associations among the vitamin D status, air pollution and obesity. Sunlight exposure accounts in humans for more than 90 % of the production of vitamin D. Among emerging factors influencing sunlight-induced synthesis of vitamin D, prospective and observational studies proved that air pollution constitutes an independent risk factor in the pathogenesis of vitamin D hypovitaminosis. In addition, environmental pollutants can affect risk of obesity when inhaled, in combination with unhealthy diet and lifestyle. In turn, obesity is closely associated with a low vitamin D status and many possible mechanisms have been proposed to explain this association. The associations of air pollution with low vitamin D status on the hand and with obesity on the other hand, could provide a rationale for considering obesity as a further link between air pollution and low vitamin D status. In this respect, a vicious cycle could operate among low vitamin D status, air pollution, and obesity, with additive detrimental effects on cardio-metabolic risk in obese individuals. Besides vitamin D supplementation, nutrient combination, used to maximize the protective effects against air pollution, might also contribute to improve the vitamin D status by attenuating the "obesogen" effects of air pollution.

Indexed as

Air PollutionHumansNutritional StatusObesityRisk FactorsSunlightVitamin DVitamin D DeficiencyVitamin DAir pollutionEnvironmental factorNutritionistObesityVitamin D

Identifiers

PMID27645613
PMCPMC5486902
OpenAlexW2522652300

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.