ReviewCurrent opinion in pediatrics2016
Indoor allergen exposure and asthma outcomes.
Review in Current opinion in pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Genetic and environmental risk factors of asthma: a narrative review.Frontiers in immunology · 2026Pooled it
- Allergen Immunotherapy with Depigmented-Polymerised Cat Allergoid Is Safe and Well-Tolerated in Patients with Allergic Rhinitis/Rhinoconjunctivitis.Journal of clinical medicine · 2025Article
- The role of housing markets in producing respiratory health disparities.Lancet regional health. Americas · 2025Review
- The Role of Environmental Exposures in Pediatric Asthma Pathogenesis: A Contemporary Narrative Review.Children (Basel, Switzerland) · 2025Review
- NOD2-NLRP3 Axis and Asthma.Journal of asthma and allergy · 2025Review
- Home and school pollutant exposure, respiratory outcomes, and influence of historical redlining.The Journal of allergy and clinical immunology · 2024Article
- A Comprehensive Look at the Development of Asthma in Children.Children (Basel, Switzerland) · 2024Review
- Factors associated with self-reported diagnosed asthma in urban and rural Malawi: Observations from a population-based study of non-communicable diseases.PLOS global public health · 2024Article
- Association of GAB1 gene with asthma susceptibility and the efficacy of inhaled corticosteroids in children.BMC pulmonary medicine · 2023Article
- Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma.Current allergy and asthma reports · 2023Review
- Environmental allergen reduction in asthma management: an overview.Frontiers in allergy · 2023Review
- Small Airway Disease in Pediatric Asthma: the Who, What, When, Where, Why, and How to Remediate. A Review and Commentary.Clinical reviews in allergy & immunology · 2022Review
- Allergen Management in Children with Type 2-High Asthma.Journal of asthma and allergy · 2022Review
- Deltamethrin Contact Exposure Mediated Toxicity and Histopathological Aberrations in Tissue Systems of Public Health Importance Cockroach SpeciesFrontiers in physiology · 2022Article
- Multi-Level Socioenvironmental Contributors to Childhood Asthma in New York City: a Cluster Analysis.Journal of urban health : bulletin of the New York Academy of Medicine · 2021Article
- Are wheezing, asthma and eczema in children associated with mother's health during pregnancy? Evidence from an Australian birth cohort.Archives of public health = Archives belges de sante publique · 2021Article
- Concordance of skin test reactivity between indoor inhalant allergens among children with allergic respiratory disease.BMC pediatrics · 2021Article
- Enhanced airway hyperresponsiveness in asthmatic children and mice with A(H1N1)pdm09 infection.Immunity, inflammation and disease · 2021Article
- Predicting Treatment Outcomes Using Explainable Machine Learning in Children with Asthma.Children (Basel, Switzerland) · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewThe aim of the present review is to discuss updates on research regarding the relationship between indoor allergen exposure and childhood asthma with a focus on clinical effects, locations of exposure, and novel treatments. RECENT
findingsRecent data continue to demonstrate that early life sensitization to indoor allergens is a predictor of asthma development later in life. Furthermore, avoidance of exposure to these allergens continues to be important especially given that the vast majority of children with asthma are sensitized to at least one indoor allergen. New research suggests that mouse allergen, more so than cockroach allergen, may be the most relevant urban allergen. Recent evidence reminds us that children are exposed to clinically important levels of indoor allergens in locations away from their home, such as schools and daycare centers. Exposure to increased levels of indoor mold in childhood has been associated with asthma development and exacerbation of current asthma; however, emerging evidence suggests that early exposure to higher fungal diversity may actually be protective for asthma development. Novel treatments have been developed that target TH2 pathways thus decreasing asthmatic responses to allergens. These therapies show promise for the treatment of severe allergic asthma refractory to avoidance strategies and standard therapies. SUMMARY: Understanding the relationship between indoor allergens and asthma outcomes is a constantly evolving study of timing, location, and amount of exposure.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.