Evidence map›Paper›PMID 27680663›Full record

SynthesisJournal of the American Heart Association2016

Dynamic Resistance Training as Stand-Alone Antihypertensive Lifestyle Therapy: A Meta-Analysis.

Hayley V MacDonald, Blair T Johnson, Tania B Huedo-Medina, Jill Livingston, Kym C Forsyth, William J Kraemer, Paulo T V Farinatti, Linda S Pescatello

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 16 pooled it
38.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 16 syntheses or guidelines pooled it, 263 citations in OpenAlex.

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  7. Effectiveness of Physical Activity and Exercise on Ambulatory Blood Pressure in Adults with Resistant Hypertension: A Systematic Review and Meta-Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hayley V MacDonaldDepartment of Kinesiology, The University of Alabama, Tuscaloosa, AL Department of Kinesiology, University of Connecticut, Storrs, CT Institute for Collaboration on Health, Intervention, and Policy (InCHIP), University of Connecticut, Storrs, CT hvmacdonald@ua.edu.
Blair T JohnsonDepartment of Psychological Sciences, University of Connecticut, Storrs, CT Institute for Collaboration on Health, Intervention, and Policy (InCHIP), University of Connecticut, Storrs, CT.
Tania B Huedo-MedinaDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT Institute for Collaboration on Health, Intervention, and Policy (InCHIP), University of Connecticut, Storrs, CT.
Jill LivingstonHomer Babbidge Library, Health Sciences, University of Connecticut, Storrs, CT.
Kym C ForsythThe Ohio State University College of Medicine, Columbus, OH.
William J KraemerDepartment of Human Sciences, The Ohio State University, Columbus, OH.
Paulo T V FarinattiInstitute of Physical Education and Sports, Universidade do Estado do Rio de Janeiro, Brazil.
Linda S PescatelloDepartment of Kinesiology, University of Connecticut, Storrs, CT Institute for Collaboration on Health, Intervention, and Policy (InCHIP), University of Connecticut, Storrs, CT.
University of Connecticut · USThe Ohio State University · USUniversidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAerobic exercise (AE) is recommended as first-line antihypertensive lifestyle therapy based on strong evidence showing that it lowers blood pressure (BP) 5 to 7 mm Hg among adults with hypertension. Because of weaker evidence showing that dynamic resistance training (RT) reduces BP 2 to 3 mm Hg among adults with hypertension, it is recommended as adjuvant lifestyle therapy to AE training. Yet, existing evidence suggests that dynamic RT can lower BP as much or more than AE. METHODS AND

resultsWe meta-analyzed 64 controlled studies (71 interventions) to determine the efficacy of dynamic RT as stand-alone antihypertensive therapy. Participants (N=2344) were white (57%), middle-aged (47.2±19.0 years), and overweight (26.8±3.4 kg/m(2)) adults with prehypertension (126.7±10.3/76.8±8.7 mm Hg); 15% were on antihypertensive medication. Overall, moderate-intensity dynamic RT was performed 2.8±0.6 days/week for 14.4±7.9 weeks and elicited small-to-moderate reductions in systolic BP (SBP; d+=-0.31; 95% CIs, -0.43, -0.19; -3.0 mm Hg) and diastolic BP (DBP; d+=-0.30; 95% CIs, -0.38, -0.18; -2.1 mm Hg) compared to controls (Ps<0.001). Greater BP reductions occurred among samples with higher resting SBP/DBP: ≈6/5 mm Hg for hypertension, ≈3/3 mm Hg for prehypertension, and ≈0/1 mm Hg for normal BP (Ps<0.023). Furthermore, nonwhite samples with hypertension experienced BP reductions that were approximately twice the magnitude of those previously reported following AE training (-14.3 mm Hg [95% CIs, -19.0, -9.4]/-10.3 mm Hg [95% CIs, -14.5, -6.2]).

conclusionsOur results indicate that for nonwhite adult samples with hypertension, dynamic RT may elicit BP reductions that are comparable to or greater than those reportedly achieved with AE training. Dynamic RT should be further investigated as a viable stand-alone therapeutic exercise option for adult populations with high BP.

Indexed as

Antihypertensive AgentsHumansHypertensionLife StylePrehypertensionRegression AnalysisResistance TrainingTreatment OutcomeAntihypertensive Agentsexercise traininghigh blood pressurehypertensionlifestylemeta‐analysissystematic review

Identifiers

PMID27680663
PMCPMC5121472
OpenAlexW2526414743

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.