Evidence map›Paper›PMID 27695671›Full record

ArticleJournal of orthopaedic translation2014

Similarities and differences in coatings for magnesium-based stents and orthopaedic implants.

Jun Ma, Marc Thompson, Nan Zhao, Donghui Zhu

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic translation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Coatings for Cardiovascular Stents-An Up-to-Date Review.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jun MaDepartment of Chemical, Biological and Bio-Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC, USA; National Science Foundation (NSF) Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC, USA.
Marc ThompsonDepartment of Chemical, Biological and Bio-Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC, USA; National Science Foundation (NSF) Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC, USA.
Nan ZhaoDepartment of Chemical, Biological and Bio-Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC, USA; National Science Foundation (NSF) Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC, USA.
Donghui ZhuDepartment of Chemical, Biological and Bio-Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC, USA; National Science Foundation (NSF) Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC, USA.
U.S. National Science Foundation · USNorth Carolina Agricultural and Technical State University · US

Funding

Brain Pericyte and Amyloid-beta Peptide InteractionSC2NS082475 · NINDS · NORTH CAROLINA AGRI & TECH ST UNIV · PI ZHU, DONGHUI · 2012 to 2014
$421k
Magnesium and alloying elements on vascular cells healthSC3GM113762 · NIGMS · NORTH CAROLINA AGRI & TECH ST UNIV · PI ZHU, DONGHUI · 2015 to 2016
$108k
NIGMS NIH HHS SC3 GM113762NINDS NIH HHS SC2 NS082475United States NIGMSUnited States NINDS
6 · The paper itself

Abstract

Magnesium (Mg)-based biodegradable materials are promising candidates for the new generation of implantable medical devices, particularly cardiovascular stents and orthopaedic implants. Mg-based cardiovascular stents represent the most innovative stent technology to date. However, these products still do not fully meet clinical requirements with regards to fast degradation rates, late restenosis, and thrombosis. Thus various surface coatings have been introduced to protect Mg-based stents from rapid corrosion and to improve biocompatibility. Similarly, different coatings have been used for orthopaedic implants, e.g., plates and pins for bone fracture fixation or as an interference screw for tendon-bone or ligament-bone insertion, to improve biocompatibility and corrosion resistance. Metal coatings, nanoporous inorganic coatings and permanent polymers have been proved to enhance corrosion resistance; however, inflammation and foreign body reactions have also been reported. By contrast, biodegradable polymers are more biocompatible in general and are favoured over permanent materials. Drugs are also loaded with biodegradable polymers to improve their performance. The key similarities and differences in coatings for Mg-based stents and orthopaedic implants are summarized.

Indexed as

BiocompatibilityBiodegradable materialsCoatingsDrug elutionMagnesium alloys

Identifiers

PMID27695671
PMCPMC5044877
OpenAlexW2100261573

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.