ReviewDiabetologia2016
Key elements of metabolomics in the study of biomarkers of diabetes.
Review in Diabetologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Changes in Plasma Metabolomic Profile Following Bariatric Surgery, Lifestyle Intervention or Diet Restriction-Insights from Human and Rat Studies.International journal of molecular sciences · 2023Trial
- Detection Limits of Blood Metabolites at Physiological Concentrations Using BenchtopNMR in biomedicine · 2026Article
- Metabolomic profiling of adenine-induced CKD: pathway interconnections and kidney injury.Toxicology research · 2025Article
- Omics experiments in Iran, a review in endocrine and metabolism disorders studies.Journal of diabetes and metabolic disorders · 2024Review
- Identifying critical age and gender-based metabolomic shifts in a Japanese population of the Tohoku Medical Megabank cohort.Scientific reports · 2024Article
- Effect of DHA-Enriched Phospholipids from Fish Roe on Rat Fecal Metabolites: Untargeted Metabolomic Analysis.Foods (Basel, Switzerland) · 2023Article
- Metabolomics profiling distinctively identified end-stage renal disease patients from chronic kidney disease patients.Scientific reports · 2023Article
- Article
- Deep Metabolic Profiling Assessment of Tissue Extraction Protocols for Three Model Organisms.Frontiers in chemistry · 2022Article
- Investigation of energy metabolic dynamism in hyperthermia-resistant ovarian and uterine cancer cells under heat stress.Scientific reports · 2021Article
- Metabolomics in Sleep, Insomnia and Sleep Apnea.International journal of molecular sciences · 2020Review
- Distinctive Metabolomics Patterns Associated With Insulin Resistance and Type 2 Diabetes Mellitus.Frontiers in molecular biosciences · 2020Article
- Metabolomics study in severe extracranial carotid artery stenosis.BMC neurology · 2019Article
- Activation of Nrf2 signaling by natural products-can it alleviate diabetes?Biotechnology advances · 2018Review
- High-throughput extraction and quantification method for targeted metabolomics in murine tissues.Metabolomics : Official journal of the Metabolomic Society · 2018Article
- New approaches beyond genetics: towards precision medicine in diabetes.Diabetologia · 2016Article
Corrections and comments
- Commented on by
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolomics is instrumental in the analysis of disease mechanisms and biomarkers of disease. The human metabolome is influenced by genetics and environmental interactions and reveals characteristic signatures of disease. Population studies with metabolomics require special study designs and care needs to be taken with pre-analytics. Gas chromatography coupled to mass spectrometry, liquid chromatography coupled to mass spectrometry or NMR are popular techniques used for metabolomic analyses in human cohorts. Metabolomics has been successfully used in the biomarker search for disease prediction and progression, for analyses of drug action and for the development of companion diagnostics. Several metabolites or metabolite classes identified by metabolomics have gained much attention in the field of diabetes research in the search for early disease detection, differentiation of progressor types and compliance with medication. This review summarises a presentation given at the 'New approaches beyond genetics' symposium at the 2015 annual meeting of the EASD. It is accompanied by another review from this symposium by Bernd Mayer (DOI: 10.1007/s00125-016-4032-2 ) and an overview by the Session Chair, Leif Groop (DOI: 10.1007/s00125-016-4014-4 ).
Indexed as
Identifiers
27714446What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.