Evidence map›Paper›PMID 27722869›Full record

ReviewAdvances in experimental medicine and biology2016

Plague Vaccines: Status and Future.

Wei Sun

Open access · greenAbstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Virulence Reduction inBiomolecules · 2025
    Article
  3. rLVS ΔHuman vaccines & immunotherapeutics · 2025
    Article
  4. Review
  5. Multiplex PCR System for the Diagnosis of Plague.Current molecular medicine · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Plague vaccines: new developments in an ongoing search.Applied microbiology and biotechnology · 2021
    Review
  12. Article
  13. Biomolecules · 2020
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Wei SunDepartment of Infectious Diseases and Pathology, College of Veterinary Medicine, University of Florida, 110880, Gainesville, FL, 32611-0880, USA. wsun8@ufl.edu.
University of Florida · US

Funding

Recombinant Attenuated Bacterial Vaccines Against Biodefense AgentsR01AI093348 · NIAID · UNIVERSITY OF FLORIDA · PI CURTISS III, ROY · 2011 to 2015
$5.0M
Live attenuated Yersinia as vaccines against pneumonic plagueR21AI095872 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SUN, WEI · 2011 to 2012
$419k
NIAID NIH HHS R01 AI093348NIAID NIH HHS R21 AI095872
6 · The paper itself

Abstract

Three major plague pandemics caused by the gram-negative bacterium Yersinia pestis have killed nearly 200 million people in human history. Due to its extreme virulence and the ease of its transmission, Y. pestis has been used purposefully for biowarfare in the past. Currently, plague epidemics are still breaking out sporadically in most of parts of the world, including the United States. Approximately 2000 cases of plague are reported each year to the World Health Organization. However, the potential use of the bacteria in modern times as an agent of bioterrorism and the emergence of a Y. pestis strain resistant to eight antibiotics bring out severe public health concerns. Therefore, prophylactic vaccination against this disease holds the brightest prospect for its long-term prevention. Here, we summarize the progress of the current vaccine development for counteracting plague.

Indexed as

EpidemicsPlague VaccineGenetic VectorsGlobal HealthHumansPlagueVaccines, AttenuatedVaccines, SubunitPlague VaccineVaccines, AttenuatedVaccines, SubunitPlagueVaccinesYersinia pestis

Identifiers

PMID27722869
PMCPMC6559729
OpenAlexW2528520137

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.