Evidence map›Paper›PMID 27746901›Full record

ArticleF1000Research2016

Illustrating and homology modeling the proteins of the Zika virus.

Sean Ekins, John Liebler, Bruno J Neves, Warren G Lewis, Megan Coffee, Rachelle Bienstock, Christopher Southan, Carolina H Andrade

Open access · goldAbstract read
In one paragraph

Article in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
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  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. The A-Z of Zika drug discovery.Drug discovery today · 2018
    Review
  13. Article
  14. Article
  15. Dengue virus-reactive CD8Nature communications · 2017
    Article
  16. Potential mechanisms of Zika-linked microcephaly.Wiley interdisciplinary reviews. Developmental biology · 2017
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Sean EkinsCollaborations in Chemistry, Fuquay-Varina, NC, USA; Collaborations Pharmaceuticals Inc., Fuquay-Varina, NC, USA; Collaborative Drug Discovery Inc, Burlingame, CA, USA.
John LieblerArt of the Cell, Guilford, CT, USA.
Bruno J NevesLabMol - Laboratory for Molecular Modeling and Drug Design, Faculty of Pharmacy, Federal University of Goias, GO, Brazil.
Warren G LewisDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Megan CoffeeThe International Rescue Committee, New York, NY, USA.
Rachelle BienstockRJB Computational Modeling LLC, Chapel Hill, NC, USA.
Christopher SouthanCentre for Integrative Physiology, University of Edinburgh, Edinburgh, UK.
Carolina H AndradeLabMol - Laboratory for Molecular Modeling and Drug Design, Faculty of Pharmacy, Federal University of Goias, GO, Brazil.
Universidade Federal de Goiás · BRCollaborative Drug Discovery (United States) · USGuilford College · USInstitute of Computational Modeling · RUInternational Rescue Committee · USUniversity of Edinburgh · GBWashington University in St. Louis · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

The Zika virus (ZIKV) is a flavivirus of the family

Indexed as

Aedes mosquitodengue virusdrug discoveryebola virusflavivirusmicrocephalyyellow feverZika virus

Identifiers

PMID27746901
PMCPMC5040154
OpenAlexW2299662534

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.