Evidence map›Paper›PMID 27763514›Full record

ReviewViruses2016

Gene Regulation and Quality Control in Murine Polyomavirus Infection.

Gordon G Carmichael

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Gordon G CarmichaelDepartment of Genetics and Genome Sciences, UCONN Health, Farmington, CT 06030, USA. carmichael@uchc.edu.
UConn Health · US

Funding

PROCESSING AND FUNCTION OF POLYOMA RNAR01CA045382 · NCI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CARMICHAEL, GORDON G · 1987 to 2015
$4.7M
NCI NIH HHS R01 CA045382
6 · The paper itself

Abstract

Murine polyomavirus (MPyV) infects mouse cells and is highly oncogenic in immunocompromised hosts and in other rodents. Its genome is a small, circular DNA molecule of just over 5000 base pairs and it encodes only seven polypeptides. While seemingly simply organized, this virus has adopted an unusual genome structure and some unusual uses of cellular quality control pathways that, together, allow an amazingly complex and varied pattern of gene regulation. In this review we discuss how MPyV leverages these various pathways to control its life cycle.

Indexed as

Gene Expression RegulationHost-Pathogen InteractionsVirus ReplicationAnimalsMicePolyomavirusnuclear retentionquality controlRNA decayRNA editingtranscription

Identifiers

PMID27763514
PMCPMC5086616
OpenAlexW2539377378

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.