Evidence map›Paper›PMID 27764767›Full record

ArticlePhysiological genomics2016

Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy.

Jeffrey J Widrick, Matthew S Alexander, Benjamin Sanchez, Devin E Gibbs, Genri Kawahara, Alan H Beggs, Louis M Kunkel

Abstract read
In one paragraph

Article in Physiological genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Modeling Sarcoglycanopathy inInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell-derived skeletal muscle in vitro.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  16. PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey J WidrickDivision of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts; jeffrey.widrick@childrens.harvard.edu.
Matthew S AlexanderDivision of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts.
Benjamin SanchezDepartment of Neurology, Division of Neuromuscular Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts.ORCID 0000-0002-1594-9847
Devin E GibbsDivision of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts.
Genri KawaharaDivision of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts.
Alan H BeggsDivision of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts.
Louis M KunkelDivision of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts.

Funding

Myogenesis Studies for FSHD BiomarkersU54HD060848 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI EMERSON, CHARLES P. · 2008 to 2017
$16.1M
SARCOMERIC PROTEINS IN NORMAL AND DISEASED MUSCLER01AR044345 · NIAMS · CHILDREN'S HOSPITAL BOSTON · PI BEGGS, ALAN H. · 1997 to 2017
$5.3M
Modulation of Jagged1/Pitpna in DMD as a means of therapyR01AR064300 · NIAMS · BOSTON CHILDREN'S HOSPITAL · PI KUNKEL, LOUIS M · 2014 to 2023
$3.9M
Genetic screening and therapies for nemaline myopathiesR01HD075802 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI BEGGS, ALAN H. · 2014 to 2018
$1.8M
NIAMS NIH HHS R01 AR044345NIAMS NIH HHS R01 AR064300NICHD NIH HHS R01 HD075802NICHD NIH HHS U54 HD060848
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDisease Models, AnimalKineticsMuscle ContractionMuscle Fibers, Fast-TwitchMuscle Fibers, Slow-TwitchMuscle, SkeletalMuscular Dystrophy, DuchenneRegression AnalysisSarcomeresTetanyZebrafishdisease modelsdystrophinmuscle contractionmuscular dystrophyzebrafish

Identifiers

PMID27764767
PMCPMC6223571

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.