Evidence map›Paper›PMID 27767372›Full record

ArticleRenal failure2017

The prognostic value of oxidative stress and inflammation in Chinese hemodialysis patients.

Zhen Wang, Chao Yu, Xin-Hua Li, Bing-Qing Deng

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhen Wanga Department of Nephrology & Rheumatology , Shanghai Tenth People's Hospital, Tongji University School of Medicine , Shanghai , China.
Chao Yua Department of Nephrology & Rheumatology , Shanghai Tenth People's Hospital, Tongji University School of Medicine , Shanghai , China.
Xin-Hua Lia Department of Nephrology & Rheumatology , Shanghai Tenth People's Hospital, Tongji University School of Medicine , Shanghai , China.
Bing-Qing Denga Department of Nephrology & Rheumatology , Shanghai Tenth People's Hospital, Tongji University School of Medicine , Shanghai , China.
Tongji University · CNShanghai Tenth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited information about oxidative stress and inflammation on the mortality of Chinese hemodialysis (HD) patients. SUBJECTS AND

methodsA total of 177 HD patients and 35 healthy controls were enrolled. Their demographic information, clinical characteristics, oxidant and inflammation markers were compared. Multivariate Cox regression analysis was used to assess the risk factors for mortality.

resultsTwenty-seven (15.3%) HD patients died during the one-year follow-up. The mean age, age ≥70 years, serum level of cardiac troponin T (cTnT), malondialdehyde (MDA) > 5 nmol/L, as well as CRP >10 mg/L and the level of interleukin (IL)-6 were significantly different between the nonsurvival and survival HD patients. Multivariate Cox's regression analysis identified age, age ≥70 years, cTnT, and IL-6 were independent predictors of mortality in HD patients.

conclusionsAge, age ≥70 years, cTnT, and IL-6 were independent predictors of mortality in Chinese HD patients. Elevated IL-6 level, instead of MDA, was predictive of poor outcome in Chinese hemodialysis patients.

Indexed as

InflammationKidney Failure, ChronicOxidative StressRenal DialysisAgedAge FactorsBiomarkersChinaC-Reactive ProteinFemaleHumansInterleukin-6MaleMalondialdehydeMiddle AgedPredictive Value of TestsBiomarkersC-Reactive ProteinInterleukin-6MalondialdehydeTroponin TEnd-stage renal diseasehemodialysisinflammationmortalityoxidative stress

Identifiers

PMID27767372
PMCPMC6014340
OpenAlexW2535138147

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.