Evidence map›Paper›PMID 27775641›Full record

ArticleInternational journal of molecular sciences2016

Genetic Heterogeneity of HER2 Amplification and Telomere Shortening in Papillary Thyroid Carcinoma.

Paola Caria, Silvia Cantara, Daniela Virginia Frau, Furio Pacini, Roberta Vanni, Tinuccia Dettori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Telomerase and Telomeres Biology in Thyroid Cancer.International journal of molecular sciences · 2019
    Review
  6. Current Knowledge in Thyroid Cancer-From Bench to Bedside.International journal of molecular sciences · 2017
    Article
  7. HER2 Analysis in Sporadic Thyroid Cancer of Follicular Cell Origin.International journal of molecular sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paola CariaDepartment of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato 09042, Italy. paola.caria@unica.it.
Silvia CantaraDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena 53100, Italy. cantara@unisi.it.
Daniela Virginia FrauDepartment of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato 09042, Italy. dvfrau@unica.it.
Furio PaciniDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena 53100, Italy. pacini8@unisi.it.
Roberta VanniDepartment of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato 09042, Italy. vanni@unica.it.
Tinuccia DettoriDepartment of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato 09042, Italy. dettorit@unica.it.
University of Cagliari · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive research is dedicated to understanding if sporadic and familial papillary thyroid carcinoma are distinct biological entities. We have previously demonstrated that familial papillary thyroid cancer (fPTC) cells exhibit short relative telomere length (RTL) in both blood and tissues and that these features may be associated with chromosome instability. Here, we investigated the frequency of

Indexed as

Gene AmplificationGenetic HeterogeneityAdultAgedAged, 80 and overAnaplastic Lymphoma KinaseCarcinoma, PapillaryErb-b2 Receptor Tyrosine KinasesETS Translocation Variant 6 ProteinFemaleGene RearrangementHumansIn Situ Hybridization, FluorescenceMaleMiddle AgedMutationALK protein, humanAnaplastic Lymphoma KinaseBRAF protein, humanERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesETS Translocation Variant 6 ProteinProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-etsProto-Oncogene Proteins c-retReceptor Protein-Tyrosine KinasesRepressor ProteinsRET protein, humanFISH (fluorescence in situ hybridization)HER2 (Human Epidermal Growth Factor Receptor 2)papillary thyroid carcinomaTelomere

Identifiers

PMID27775641
PMCPMC5085783
OpenAlexW2532048767

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.