Evidence map›Paper›PMID 27776508›Full record

ArticleBMC complementary and alternative medicine2016

Protective effects of Fraxinus xanthoxyloides (Wall.) leaves against CCl

Tahira Younis, Muhammad Rashid Khan, Moniba Sajid

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. RETRACTED: Zafar et al.Pharmaceutics · 2025
    Article
  4. Article
  5. Targeting Mitochondrial Metabolism in Prostate Cancer with Triterpenoids.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Antioxidant, anti-inflammatory and anti-fibrotic effects ofExperimental and therapeutic medicine · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tahira YounisDepartment of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Muhammad Rashid KhanDepartment of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan. mrkhanqau@yahoo.com.
Moniba SajidDepartment of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Quaid-i-Azam University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeaves and root bark of Fraxinus xanthoxyloides Wall. (Oleaceae) are used locally for the treatment of jaundice, malaria and pneumonia. Decoction of stem, twigs and bark is used in pain, internal injuries, rheumatism and in bone fracture. In this investigation we have evaluated the methanol extract of leaves for its hepatoprotective potential against CCl

methodsPowder of F. xanthoxyloides leaves was extracted with methanol (FXM) and subjected for the determination of polyphenolics through HPLC-DAD analysis. Sprague-Dawley (Rattus novergicus) male rats were divided into eight groups (six rats in each). Group I: non-treated control; Group II: vehicle treated (DMSO plus olive oil) while Group III- VI treated with 1 ml/kg body weight (bw) of CCl

resultsHPLC-DAD analysis of FXM revealed the existence of rutin and caffeic acid. In CCl

conclusionResults of present investigation revealed that F. xanthoxyloides leaves possibly protect the liver against CCl

Indexed as

AnimalsAntioxidantsBiomarkersCarbon TetrachlorideChemical and Drug Induced Liver InjuryFraxinusLipid PeroxidationLiverMaleOxidative StressPlant ExtractsPlant LeavesRatsRats, Sprague-DawleyAntioxidantsBiomarkersCarbon TetrachloridePlant ExtractsAntioxidantCCl4Fraxinus xanthoxyloidesLipid peroxidationLiverPhenolics

Identifiers

PMID27776508
PMCPMC5078913
OpenAlexW2534855805

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.