Evidence map›Paper›PMID 27789073›Full record

ReviewSeminars in oncology nursing2016

Cancer Symptom Cluster Management.

Kristine L Kwekkeboom

2 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Seminars in oncology nursing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 90 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 10 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03823456 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Self-acupressure for Cancer-related Symptom Cluster of Insomnia, Depression, and Anxiety in Cancer Patients: a Feasibility Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2018 to 2019Enrolled114ConditionsInsomnia, Anxiety, DepressionArmsSelf-acupressure, Sham Self-acupressure
NCT07481903 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Acupuncture on Psychoneurological Symptom Cluster in Breast Cancer Survivors

TypeinterventionalSponsorFirst Teaching Hospital of Tianjin University of Traditional Chinese MedicineRan2026 to 2028Enrolled228ConditionsPsychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline), Pain, Insomnia, AnxietyArmselectroacupuncture, sham electroacupuncture
3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 10 syntheses or guidelines pooled it, 161 citations in OpenAlex.

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  13. Symptom response analysis of a randomized controlled trial of reflexology for symptom management among women with advanced breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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  15. Gastrointestinal symptom profiles after resection of esophageal or gastric cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kristine L Kwekkeboom
University of Wisconsin–Madison · US

Funding

A Brief Patient-Controlled Intervention for a Symptom Cluster in Advanced CancerR01NR013468 · NINR · UNIVERSITY OF WISCONSIN-MADISON · PI KWEKKEBOOM, KRISTINE L · 2013 to 2016
$2.0M
NINR NIH HHS R01 NR013468
6 · The paper itself

Abstract

objectivesTo discuss the importance of cancer symptom clusters in clinical practice, review evidence for symptom cluster interventions, and make recommendations for symptom cluster identification, patient education, and management in clinical practice. DATA SOURCES: Primary research and review articles identified through CINAHL, PubMed, and PsycINFO databases.

conclusionSeveral studies have investigated interventions for multi-symptom management or have evaluated the secondary effects of a single-symptom intervention on related symptoms. To date, only five studies have tested an intervention designed to manage a specific cancer symptom cluster. Those studies used nonpharmacologic approaches (psycho-education, cognitive-behavioral strategies, and acupressure) to address the pain, fatigue, and sleep disturbance symptom cluster, or the respiratory distress symptom cluster with some initial evidence of success. Further development and efficacy testing of symptom cluster interventions is needed. IMPLICATIONS FOR NURSING PRACTICE: Clinical practice can be guided by knowledge of individual and multi-symptom management, and clinical judgment regarding possible etiologies of cancer symptom clusters. Clinicians should be aware of co-occurring symptoms in their patients, educate and involve patients in identifying symptom clusters and aggravating/alleviating factors, and coordinate treatment recommendations using strategies that are likely to be beneficial across symptoms.

Indexed as

Symptom AssessmentFatigueHumansNeoplasmsPainSleep Wake DisordersSyndromeclinical practicepatient educationsymptom clustersymptom managementtherapeutics

Identifiers

PMID27789073
PMCPMC5143160
OpenAlexW2538492664

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.