← Other glucose-lowering × kidney outcomes

TrialPloS one2016

Renal Outcomes of Pioglitazone Compared with Acarbose in Diabetic Patients: A Randomized Controlled Study.

Yu-Hsin Chen et al.PubMed ↗Full text ↗Publisher ↗

  • Pioglitazoneno clear effectLower kidney function, no range given.No ranges given.

What the trial testedas reported · 30 people · 2016

No range given

Reported higher kidney outcomes, no range given

+85.0

As reported

difference 85, no interval

No range given

Reported lower kidney function, no range given

−7.00

pioglitazone vs acarbose

As reported

difference −7, no interval · the paper's word: eGFR

No range given

Reported higher kidney outcomes, no range given

+16.0mL/min/1.73 m2

As reported

difference 16 mL/min/1.73 m2, no interval

Who was studied, and how

200people in the The Effects of Thiazolidinedione on the Diabetic Retinopathy and Nephropathy trial, from 2010
30of them with kidney disease, in this paper

The trial randomly assignedassigned by chance

pioglitazone
acarbose

Reported lower kidney function, no range given−7.00

randomised

the abstract, start to end

… changes in UACR were -18 ± 104 and 12 ± 85 (p = 0.25, between groups) for …

The mean changes in eGFR were 0 ± 14 and -7 ± 16 mL/min/1.73 m2 (p = 0.09, …

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Kidney outcomes
85
EGFRpioglitazone vs acarbose
−7
Kidney outcomes
16
ThiazolidinedionesOther glucose-loweringKidney outcomes
1 / 4

8 papers cite it

2016
2017
2018
2019
2020
2021
2022
2023
2024
this paperpooled ittrialcites it

The trial

Full record →Abstract, authors, funding and every citing paper · PMID 27812149