Evidence map›Paper›PMID 27827990›Full record

ArticleVaccines2016

Edwardsiella tarda OmpA Encapsulated in Chitosan Nanoparticles Shows Superior Protection over Inactivated Whole Cell Vaccine in Orally Vaccinated Fringed-Lipped Peninsula Carp (Labeo fimbriatus).

Saurabh Dubey, Kiran Avadhani, Srinivas Mutalik, Sangeetha Madambithara Sivadasan, Biswajit Maiti, Shivani Kallappa Girisha, Moleyur Nagarajappa Venugopal, Stephen Mutoloki, Øystein Evensen, Indrani Karunasagar and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Current Progress and Challenges in the Study of Adjuvants for Oral Vaccines.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  6. Review
  7. Article
  8. Review
  9. Synthesis ofVaccines · 2021
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Teleosts Genomics: Progress and Prospects in Disease Prevention and Control.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Saurabh DubeyDepartment of Fisheries Microbiology, Karnataka Veterinary, Animal & Fisheries Sciences University, College of Fisheries, Mangalore 575002, India. saurabh.dubey@nmbu.no.
Kiran AvadhaniDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal 576104, Karnataka State, India. kirankle84@gmail.com.
Srinivas MutalikDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal 576104, Karnataka State, India. ssmutalik@yahoo.com.
Sangeetha Madambithara SivadasanDepartment of Fisheries Microbiology, Karnataka Veterinary, Animal & Fisheries Sciences University, College of Fisheries, Mangalore 575002, India. sangeethasivadas888@gmail.com.
Biswajit MaitiUNESCO MIRCEN for Marine Biotechnology, Nitte University Centre for Science Education and Research, Paneer Campus, Deralakatte, Mangalore 575018, India. maiti.b@nitte.edu.in.
Shivani Kallappa GirishaDepartment of Fisheries Microbiology, Karnataka Veterinary, Animal & Fisheries Sciences University, College of Fisheries, Mangalore 575002, India. skgirisha@gmail.com.
Moleyur Nagarajappa VenugopalDepartment of Fisheries Microbiology, Karnataka Veterinary, Animal & Fisheries Sciences University, College of Fisheries, Mangalore 575002, India. mnvenu@rediffmail.com.
Stephen MutolokiNorwegian University of Life Sciences, Faculty of Veterinary Medicine, Department of Basic Sciences and Aquatic Medicine, Section of Aquatic Medicine and Nutrition, Adamstuen Campus, Ullevålseveien 72, P.O. Box 8146, NO-0033 Dep, Oslo 0454, Norway. stephen.mutoloki@nmbu.no.
Øystein EvensenNorwegian University of Life Sciences, Faculty of Veterinary Medicine, Department of Basic Sciences and Aquatic Medicine, Section of Aquatic Medicine and Nutrition, Adamstuen Campus, Ullevålseveien 72, P.O. Box 8146, NO-0033 Dep, Oslo 0454, Norway. oystein.evensen@nmbu.no.
Indrani KarunasagarUNESCO MIRCEN for Marine Biotechnology, Nitte University Centre for Science Education and Research, Paneer Campus, Deralakatte, Mangalore 575018, India. indrani.karunasagar@nitte.edu.in.
Hetron Mweemba Munang’anduNorwegian University of Life Sciences, Faculty of Veterinary Medicine, Department of Basic Sciences and Aquatic Medicine, Section of Aquatic Medicine and Nutrition, Adamstuen Campus, Ullevålseveien 72, P.O. Box 8146, NO-0033 Dep, Oslo 0454, Norway. hetroney.mweemba.munangandu@nmbu.no.
Karnataka Veterinary Animal and Fisheries Sciences University · INNorwegian University of Life Sciences · NOManipal Academy of Higher Education · INNitte University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of oral vaccination in finfish has lagged behind injectable vaccines for a long time as oral vaccines fall short of injection vaccines in conferring protective immunity. Biodegradable polymeric nanoparticles (NPs) have shown potential to serve as antigen delivery systems for oral vaccines. In this study the recombinant outer membrane protein A (rOmpA) of

Indexed as

carpchitosannanoparticleoralouter membrane proteinvaccination

Identifiers

PMID27827990
PMCPMC5192360
OpenAlexW2552375428

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.