ArticlePloS one2016
Cutoff Point of HbA1c for Diagnosis of Diabetes Mellitus in Chinese Individuals.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The value of glycosylated hemoglobin in the diagnosis of diabetic retinopathy: a systematic review and Meta-analysis.BMC endocrine disorders · 2021Pooled it
- Total cholesterol, high-density lipoprotein, and glucose (CHG) index and diabetic retinopathy in middle-aged and elderly Chinese adults with diabetes: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Cut-off value of glycated hemoglobin A1c for detecting diabetic retinopathy in the Chinese population.World journal of diabetes · 2024Article
- Revised Glycemic Index for Diagnosing and Monitoring of Diabetes Mellitus in South Indian Population.Cureus · 2022Article
- Epidemiology, health policy and public health implications of visual impairment and age-related eye diseases in mainland China.Frontiers in public health · 2022Review
- Discordance between Fasting Plasma Glucose (FPG) and HbA1c in Diagnosing Diabetes and Pre-diabetes in The Malaysian Cohort.Journal of the ASEAN Federation of Endocrine Societies · 2021Article
- The diagnostic accuracy of HbA1c in detecting gestational diabetes mellitus among Chinese pregnant individuals.Annals of translational medicine · 2020Article
- A Comparison of the Association of Fasting Plasma Glucose and HbA1c Levels with Diabetic Retinopathy in Japanese Men.Journal of diabetes research · 2020Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of the present study was to find the optimal threshold of glycated hemoglobin (HbA1c) for diagnosis of diabetes mellitus in Chinese individuals.
methodsA total of 8 391 subjects (including 2 133 men and 6 258 women) aged 40-90 years with gradable retinal photographs were recruited. The relationship between HbA1c and diabetic retinopathy (DR) was examined. Receiver operating characteristic (ROC) curves were used to find the optimal threshold of HbA1c in screening DR and diagnosing diabetes.
resultsHbA1c values in patients with DR were significantly higher than in those with no DR. The ROC curve for HbA1c had an area under the curve of 0.881 (95%CI 0.857-0.905; P = 0.000). HbA1c at a cutoff of 6.5% had a high sensitivity (80.6%) and specificity (86.9%) for detecting DR.
conclusionsHbA1c can be used to diagnose diabetes in a Chinese population, and the optimal HbA1c cutoff point for diagnosis is 6.5%.
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Registered trials
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