Evidence map›Paper›PMID 27878659›Full record

ReviewNeurochemical research2017

Neural Signaling Metabolites May Modulate Energy Use in Hibernation.

Kelly L Drew, Carla Frare, Sarah A Rice

Open access · greenAbstract readReview
In one paragraph

Review in Neurochemical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kelly L DrewDepartment of Chemistry and Biochemistry, Institute of Arctic Biology, University of Alaska Fairbanks, 902 N. Koyukuk Drive, Fairbanks, AK, 99775, USA. kdrew@alaska.edu.ORCID http://orcid.org/0000-0002-2436-5720
Carla FrareDepartment of Chemistry and Biochemistry, Institute of Arctic Biology, University of Alaska Fairbanks, 902 N. Koyukuk Drive, Fairbanks, AK, 99775, USA.
Sarah A RiceDepartment of Chemistry and Biochemistry, Institute of Arctic Biology, University of Alaska Fairbanks, 902 N. Koyukuk Drive, Fairbanks, AK, 99775, USA.
University of Alaska Fairbanks · US

Funding

Targeting Central A1 Adenosine Receptors Induces Hypothermia for StrokeR15NS070779 · NINDS · UNIVERSITY OF ALASKA FAIRBANKS · PI DREW, KELLY L · 2010 to 2014
$949k
Brain regions involved in seasonally dependent A1AR agonist-induced torporR03NS081637 · NINDS · UNIVERSITY OF ALASKA FAIRBANKS · PI DREW, KELLY L · 2013 to 2014
$149k
NINDS NIH HHS R03 NS081637NINDS NIH HHS R15 NS070779
6 · The paper itself

Abstract

Despite an epidemic in obesity and metabolic syndrome limited means exist to effect adiposity or metabolic rate other than life style changes. Here we review evidence that neural signaling metabolites may modulate thermoregulatory pathways and offer novel means to fine tune energy use. We extend prior reviews on mechanisms that regulate thermogenesis and energy use in hibernation by focusing primarily on the neural signaling metabolites adenosine, AMP and glutamate.

Indexed as

AnimalsBody TemperatureBody Temperature RegulationEnergy MetabolismHibernationHumansNeuronsSignal TransductionAdenosineArctic ground squirrelGlutamateObesityThermoregulationTorpor

Identifiers

PMID27878659
PMCPMC5284051
OpenAlexW2556713997

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.