Evidence map›Paper›PMID 27887589›Full record

SynthesisBMC neurology2016

Guidelines for dementia or Parkinson's disease with depression or anxiety: a systematic review.

Zahra Goodarzi, Bria Mele, Selynne Guo, Heather Hanson, Nathalie Jette, Scott Patten, Tamara Pringsheim, Jayna Holroyd-Leduc

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Article
  6. Article
  7. Article
  8. Exploring depression in Alzheimer's disease: an Italian Delphi Consensus on phenomenology, diagnosis, and management.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  9. Parkinson disease primer, part 1: diagnosis.Canadian family physician Medecin de famille canadien · 2023
    Article
  10. Characteristics and Outcome Determinants of Hospitalized Older Patients with Cognitive Dysfunction.International journal of environmental research and public health · 2022
    Article
  11. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Zahra GoodarziDepartment of Community Health Sciences, University of Calgary, Calgary, Canada. [email protected].
Bria MeleDepartment of Community Health Sciences, University of Calgary, Calgary, Canada.
Selynne GuoFaculty of Medicine, Undergraduate Medical Education, University of Toronto, Toronto, Canada.
Heather HansonDepartment of Community Health Sciences, University of Calgary, Calgary, Canada.
Nathalie JetteDepartment of Community Health Sciences, University of Calgary, Calgary, Canada.
Scott PattenDepartment of Community Health Sciences, University of Calgary, Calgary, Canada.
Tamara PringsheimDepartment of Community Health Sciences, University of Calgary, Calgary, Canada.
Jayna Holroyd-LeducDepartment of Community Health Sciences, University of Calgary, Calgary, Canada.
University of Calgary · CAAlberta Health Services · CACalgary Laboratory Services · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression and anxiety remain under-diagnosed and under-treated in those with neurologic diseases such as dementia or Parkinson's Disease (PD). Our objectives were to first, to provide a synthesis of high quality guidelines available for the identification and management of depression or anxiety in those with dementia or PD. Second, to identify areas for improvement for future guidelines.

methodsWe searched MEDLINE, PsycINFO, and EMBASE (2009 to July 24, 2015), grey literature (83 sources; July 24-Sept 6, 2015), and bibliographies of included studies. Included studies were evaluated for quality by four independent reviewers the AGREE II tool. Guideline characteristics, statements and recommendations relevant to depression or anxiety for dementia and PD were then extracted. (PROSPERO CRD: 42016014584)

results8121 citations were reviewed with 31 full text articles included for assessment with the AGREE II tool. 17 were of sufficient quality for inclusion. Mean overall quality scores were between 4.25 to 6.5. Domain scores were lowest in the areas of stakeholder involvement, applicability, and editorial independence. Recommendations for the screening and diagnosis of depression were found for PD and dementia. There was little evidence to guide diagnosis or management of anxiety. Non-pharmacologic therapies were recommended for dementia patients. Most advocated pharmacologic treatment for depression, for both PD and dementia, but did not specify an agent due to lack of evidence.

conclusionsThe available recent high quality guidelines outline several recommendations for the management of comorbid depression or anxiety in PD or dementia. However there remain significant gaps in the evidence.

Indexed as

Practice Guidelines as TopicAnxietyDementiaDepressionHumansParkinson DiseaseAnxietyDementiaDepressionGuidelinesParkinson’s Disease

Identifiers

PMID27887589
PMCPMC5124305
OpenAlexW2549683405

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.