Evidence map›Paper›PMID 27909770›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2017

The natural history of takotsubo syndrome: a two-year follow-up study with myocardial sympathetic and perfusion G-SPECT imaging.

Stelvio Sestini, Francesco Pestelli, Mario Leoncini, Francesco Bellandi, Christian Mazzeo, Luigi Mansi, Ignasi Carrio, Antonio Castagnoli

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Sympathetic nerve activity and response to physiological stress in Takotsubo syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Trial
  2. Review
  3. Article
  4. Review
  5. Novel Imaging and Genetic Risk Markers in Takotsubo Syndrome.Frontiers in cardiovascular medicine · 2021
    Review
  6. The role of multimodality imaging in takotsubo cardiomyopathy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Review
  7. Article
  8. Roles of cardiac sympathetic neuroimaging in autonomic medicine.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Stelvio SestiniDeptartment of Diagnostic Imaging, Nuclear Medicine Unit, N.O.P. - S. Stefano, U.S.L. Toscana Centro, via Suor Niccolina Infermiera 20, 59100, Prato, Italy. stelvio.sestini@uslcentro.toscana.it.
Francesco PestelliDeptartment of Internal Medicine, Cardiovascular Unit, N.O.P. - S. Stefano, U.S.L, Toscana Centro, Prato, Italy.
Mario LeonciniDeptartment of Internal Medicine, Cardiovascular Unit, N.O.P. - S. Stefano, U.S.L, Toscana Centro, Prato, Italy.
Francesco BellandiDeptartment of Internal Medicine, Cardiovascular Unit, N.O.P. - S. Stefano, U.S.L, Toscana Centro, Prato, Italy.
Christian MazzeoDeptartment of Diagnostic Imaging, Nuclear Medicine Unit, N.O.P. - S. Stefano, U.S.L. Toscana Centro, via Suor Niccolina Infermiera 20, 59100, Prato, Italy.
Luigi MansiDeptartment of Diagnostic Imaging, Nuclear Medicine Unit, University II Naples, Naples, Italy.ORCID http://orcid.org/0000-0001-8258-5134
Ignasi CarrioNuclear Medicine, Hospital Sant Pau, Barcelona, Spain.
Antonio CastagnoliDeptartment of Diagnostic Imaging, Nuclear Medicine Unit, N.O.P. - S. Stefano, U.S.L. Toscana Centro, via Suor Niccolina Infermiera 20, 59100, Prato, Italy.
Azienda Usl Toscana Centro · ITHospital de Sant Pau · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate changes in sympathetic activity, perfusion, and left ventricular (LV) functionality in takotsubo cardiomyopathy (TTC) patients from onset (T

methodsTwenty-two patients (70 ± 11 years) underwent serial gated single photon emission tomography (G-SPECT) studies with

resultsPatients presented at T

conclusionOutcome for TTC is not limited to a reversible contractile and perfusion abnormalities, but it includes residual adrenergic dysfunction, depending on the level of adrenergic impairment and age of patients at onset. The number of patients, as well as degree of perfusion abnormalities were found to be higher than those previously reported possibly depending on the time-interval between hospital admission and perfusion scan.

Indexed as

AgedAged, 80 and overAutonomic Nervous System DiseasesDisease ProgressionEchocardiographyFemaleFollow-Up StudiesGated Blood-Pool ImagingHumansLongitudinal StudiesMaleMiddle AgedMyocardial Perfusion ImagingStress, PsychologicalTakotsubo CardiomyopathyVentricular Dysfunction, LeftmIBGMyocardial perfusionTakotsubo syndrome

Identifiers

PMID27909770
OpenAlexW2557519604

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.