Evidence map›Paper›PMID 27917205›Full record

ArticleAfrican health sciences2016

Impact of weight loss on oxidative stress and inflammatory cytokines in obese type 2 diabetic patients.

Shehab M Abd El-Kader, Mohammed H Saiem Al-Dahr

Open access · diamondAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in African health sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  10. Efficacy of a Homemade Very Low Calorie Diet to Achieve Prevention or Remission of Type 2 Diabetes: A Pilot Study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shehab M Abd El-KaderDepartment of Physical Therapy, Faculty of Applied Medical Sciences, King Abdulaziz University.
Mohammed H Saiem Al-DahrDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University.
King Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 diabetes mellitus is associated with abnormal markers of inflammatory cytokines and oxidative stress markers. Although, these abnormalities could be modulated with weight reduction; there is limitation in clinical studies that have addressed the beneficial effects of weight reduction in modulating biomarkers of inflammatory cytokines and oxidative stress for obesity associated with type 2 diabetes mellitus.

objectiveThis study was designed to detect the effects of weight loss on the inflammatory cytokines, oxidative stress markers in obese type 2 diabetic patients. MATERIAL AND

methodsEighty obese patients with type 2 diabetes mellitus, their age ranged from 35-57 years and their body mass index ranged from 31-35 kg/m

resultsThe mean values of body mass index (BMI), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), C-reactive protein (sCRP), conjugated dienes (CD) and malondialdehyde (MDA) were significantly decreased, while the mean values of glutathione peroxidase (GPx), superoxide dismutase (SOD) and glutathione (GSH) were significantly increased in patients of group (A), while changes were not significant in group (B). Also, there were significant differences between mean levels of the investigated parameters in group (A) and group (B) at the end of the study.

conclusionWeight loss ameliorates inflammatory cytokines and oxidative stress markers in obese type 2 diabetic patients.

Indexed as

Diabetes Mellitus, Type 2ObesityAdultC-Reactive ProteinCytokinesFemaleHumansMaleMiddle AgedOxidative StressWeight LossC-Reactive ProteinCytokinescytokinesobesityoxidative stressType 2 diabetesweight reduction

Identifiers

PMID27917205
PMCPMC5111974
OpenAlexW2536074916

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.