ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2017
Recurrence and survival factors analysis of 171 cases of sacral chordoma in a single institute.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Mayo Clinic classification of presacral tumors: evolution of classifications and systematic review of pathologies.BJS open · 2026Pooled it
- Comparative analysis of surgical outcomes and prognostic factors between primary and recurrent sacral chordomas.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Recurrence Patterns After Resection of Sacral Chordoma: Toward an Optimized Postoperative Target Volume Definition.Cancers · 2025Article
- Multidisciplinary En-Bloc Resection of Sacral Chordoma: A Narrative Review and Illustrative Case.Journal of clinical medicine · 2025Review
- Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth.Acta neuropathologica communications · 2024Article
- Clinical characteristics and predisposing factors of lung metastasis in sacral chordoma: a cross-sectional cohort study of 221 cases.Frontiers in oncology · 2024Article
- Partial sacrectomy with patient-specific osteotomy guides.North American Spine Society journal · 2021Article
- Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature.Molecular and clinical oncology · 2021Article
- Recurrent Sacral Chordoma: A Case Report.JNMA; journal of the Nepal Medical Association · 2020Article
- A case-control study of computer navigation assisted resection of primary sacral chordoma above sacrum 3 level.Journal of bone oncology · 2020Article
- The role of TNF-α in chordoma progression and inflammatory pathways.Cellular oncology (Dordrecht, Netherlands) · 2019Article
- Role of diffusion-weighted imaging in monitoring treatment response following high-intensity focused ultrasound ablation of recurrent sacral chordoma.Radiology case reports · 2019Article
- Conditional survival and changing risk profile in patients with chordoma: a population-based longitudinal cohort study.Journal of orthopaedic surgery and research · 2019Article
- Prognostic significance of pretreatment plasma D-dimer levels in patients with spinal chordoma: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Article
- Rectotumoral fistula formation occurring more than 5 years after carbon ion radiotherapy for sacral chordoma: A case report.Molecular and clinical oncology · 2019Article
- Defining preoperative imaging findings of sacral chordomas associated with decreased overall survival and local recurrence.Journal of spine surgery (Hong Kong) · 2019Article
- Cryosurgery in the excision of a giant local recurrent sacral chordoma: a case report and literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Review
- The Michel Benoist and Robert Mulholland yearly European Spine Journal Review: a survey of the "surgical and research" articles in the European Spine Journal, 2017.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate postoperative recurrence, survival and metastasis results and related factors of sacral chordoma.
methodsBetween 1978 and 2013, a total of 171 patients with sacral chordoma were diagnosed at our institution and 162 cases underwent operation. The clinical characteristics, treatment and outcomes of all these patients were reviewed.
resultsThe 3-year recurrence free survival rate was 83.1%. The median recurrence free survival time was 73 ± 7.8 months. Tumor level in sacrum and surgical margin were significant factors influencing recurrence. Recurrence was significant factor influencing metastasis. One hundred and fifty-seven cases were followed up for an average of 55.6 months. 135 cases (86%) survived, 37 cases (23.6%) developed recurrence, and 17 cases (10.8%) developed metastasis. The overall 5- and 10-year survival rate was 88.3% and 59.6%, respectively. Age (p = 0.037) and metastasis (p = 0.001) were significant factors influencing survival. The 3-year recurrence free survival rate was 80.1%. The median recurrence free survival time was 69 ± 12.7 months. Tumor level in sacrum (p = 0.035) and surgical margin (p = 0.009) were significant factors influencing recurrence. Seventeen cases (10.8%) had metastasis. Recurrence (p = 0.016) was significant factors influencing metastasis.
conclusionsSacral chordoma tended to occur in elderly male patients and locate below sacral 3 level. The recurrence rate was high, especially for tumor above sacral 3 level. Wide surgical margin is very important for good local control. The patients with metastasis had poor prognosis.
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