Evidence map›Paper›PMID 27974308›Full record

Trial reportThe American journal of clinical nutrition2017

Prospective associations between problematic eating attitudes in midchildhood and the future onset of adolescent obesity and high blood pressure.

Kaitlin H Wade, Michael S Kramer, Emily Oken, Nicholas J Timpson, Oleg Skugarevsky, Rita Patel, Natalia Bogdanovich, Konstantin Vilchuck, George Davey Smith, Jennifer Thompson and 1 more

Registry-linked trialOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01561612 (Breastfeeding Promotion RCT and Child Metabolic Syndrome), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01561612 nacompletednot on this map

Breastfeeding Promotion RCT and Child Metabolic Syndrome

TypeinterventionalSponsorHarvard Pilgrim Health CareRan1996Enrolled17,046ConditionsEffect of Breastfeeding on Maternal and Child Health OutcomesArmsBreastfeeding promotion and support
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  6. Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Kaitlin H WadeSchool of Social and Community Medicine, Faculty of Health Sciences, kaitlin.wade@bristol.ac.uk.
Michael S KramerDepartments of Pediatrics and.
Emily OkenDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA.
Nicholas J TimpsonSchool of Social and Community Medicine, Faculty of Health Sciences.
Oleg SkugarevskyDepartment of Psychiatry and Medical Psychology, Belarusian State Medical University, Minsk, Belarus; and.
Rita PatelSchool of Social and Community Medicine, Faculty of Health Sciences.
Natalia BogdanovichNational Research and Applied Medicine Mother and Child Centre, Minsk, Belarus.
Konstantin VilchuckNational Research and Applied Medicine Mother and Child Centre, Minsk, Belarus.
George Davey SmithSchool of Social and Community Medicine, Faculty of Health Sciences.
Jennifer ThompsonDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA.
Richard M MartinSchool of Social and Community Medicine, Faculty of Health Sciences.ORCID 0000-0002-7992-7719
Harvard University · USMRC Integrative Epidemiology UnitBelarusian State Medical University · BYMcGill University · CANational Health Service · GBUniversity of Bristol · GB

Funding

Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Breastfeeding RCT: Adolescent Neurocognitive and Respiratory FunctionR01HD050758 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI MARTIN, RICHARD MICHAEL, OKEN, EMILY · 2007 to 2014
$3.0M
Patient-oriented Research in Maternal Perinatal Overnutrition and Child AdiposityK24HD069408 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2011 to 2015
$844k
Medical Research Council MC_UU_12013/3NICHD NIH HHS K24 HD069408NICHD NIH HHS R01 HD050758NIDDK NIH HHS P30 DK092924Wellcome Trust 096989/Z11/ZWellcome Trust 202802/Z/16/Z
6 · The paper itself

Abstract

backgroundClinically diagnosed eating disorders may have adverse cardiometabolic consequences, including overweight or obesity and high blood pressure. However, the link between problematic eating attitudes in early adolescence, which can lead to disordered eating behaviors, and future cardiometabolic health is, to our knowledge, unknown.

objectiveWe assessed whether variations in midchildhood eating attitudes influence the future development of overweight or obesity and high blood pressure.

designOf 17,046 children who participated in the Promotion of Breastfeeding Intervention Trial (PROBIT), we included 13,557 participants (79.5% response rate) who completed the Children's Eating Attitudes Test (ChEAT) at age 11.5 y and in whom we measured adiposity and blood pressure at ages 6.5, 11.5, and 16 y. We assessed whether ChEAT scores ≥85th percentile (indicative of problematic eating attitudes) compared with scores <85th percentile at age 11.5 y were associated with new-onset overweight, obesity, high systolic blood pressure, or high diastolic blood pressure between midchildhood and early adolescence.

resultsAfter controlling for baseline sociodemographic confounders, we observed positive associations of problematic eating attitudes at age 11.5 y with new-onset obesity (OR: 2.18; 95% CI: 1.58, 3.02), new-onset high systolic blood pressure (OR: 1.34; 95% CI: 1.05, 1.70), and new-onset high diastolic blood pressure (OR: 1.25; 95% CI: 0.99, 1.58) at age 16 y. After further controlling for body mass index at age 6.5 y, problematic eating attitudes remained positively associated with new-onset obesity (OR: 1.80; 95% CI: 1.28, 2.53); however, associations with new-onset high blood pressure were attenuated (OR: 1.14; 95% CI: 0.89, 1.45 and OR: 1.09; 95% CI: 0.86, 1.39 for new-onset systolic and diastolic blood pressure, respectively).

conclusionsProblematic eating attitudes in midchildhood seem to be related to the development of obesity in adolescence, a relatively novel observation with potentially important public health implications for obesity control. PROBIT was registered at clinicaltrials.gov as NCT01561612 and isrctn.com as ISRCTN37687716.

Indexed as

Health Knowledge, Attitudes, PracticeAdiposityAdolescentBlood PressureBody Mass IndexChildCluster AnalysisFeeding BehaviorFemaleFollow-Up StudiesHumansHypertensionMaleMultivariate AnalysisOverweightPediatric Obesityadiposityadolescentsblood pressureproblematic eating attitudesprospective

Identifiers

PMID27974308
PMCPMC5267301
OpenAlexW2566652515

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.