Evidence map›Paper›PMID 27974503›Full record

ArticleGenetics2017

Traffic Through the Trans-Golgi Network and the Endosomal System Requires Collaboration Between Exomer and Clathrin Adaptors in Fission Yeast.

Marta Hoya, Francisco Yanguas, Sandra Moro, Cristina Prescianotto-Baschong, Cristina Doncel, Nagore de León, M-Ángeles Curto, Anne Spang, M-Henar Valdivieso

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Virus infection and vesicle trafficking.Frontiers in immunology · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Chitin Synthesis in Yeast: A Matter of Trafficking.International journal of molecular sciences · 2022
    Review
  6. Exomer complex regulates protein traffic at the TGN through differential interactions with cargos and clathrin adaptor complexes.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Spatiotemporal dissection of theJournal of cell science · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Marta HoyaDepartment of Microbiology and Genetics, Institute of Functional Biology and Genomics (IBFG), University of Salamanca, Consejo Superior de Investigaciones Científicas (CSIC), 37007, Spain.
Francisco YanguasDepartment of Microbiology and Genetics, Institute of Functional Biology and Genomics (IBFG), University of Salamanca, Consejo Superior de Investigaciones Científicas (CSIC), 37007, Spain.
Sandra MoroDepartment of Microbiology and Genetics, Institute of Functional Biology and Genomics (IBFG), University of Salamanca, Consejo Superior de Investigaciones Científicas (CSIC), 37007, Spain.
Cristina Prescianotto-BaschongBiozentrum, University of Basel, CH-4056, Switzerland.
Cristina DoncelDepartment of Microbiology and Genetics, Institute of Functional Biology and Genomics (IBFG), University of Salamanca, Consejo Superior de Investigaciones Científicas (CSIC), 37007, Spain.
Nagore de LeónDepartment of Microbiology and Genetics, Institute of Functional Biology and Genomics (IBFG), University of Salamanca, Consejo Superior de Investigaciones Científicas (CSIC), 37007, Spain.
M-Ángeles CurtoDepartment of Microbiology and Genetics, Institute of Functional Biology and Genomics (IBFG), University of Salamanca, Consejo Superior de Investigaciones Científicas (CSIC), 37007, Spain.
Anne SpangBiozentrum, University of Basel, CH-4056, Switzerland.
M-Henar ValdiviesoDepartment of Microbiology and Genetics, Institute of Functional Biology and Genomics (IBFG), University of Salamanca, Consejo Superior de Investigaciones Científicas (CSIC), 37007, Spain henar@usal.es.ORCID 0000-0002-6857-7493
Consejo Superior de Investigaciones Científicas · ESUniversity of Basel · CHInstituto de Biología Funcional y Genómica · ESUniversidad de Salamanca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite its biological and medical relevance, traffic from the Golgi to the plasma membrane (PM) is one of the least understood steps of secretion. Exomer is a protein complex that mediates the trafficking of certain cargoes from the trans-Golgi network/early endosomes to the PM in budding yeast. Here, we show that in Schizosaccharomyces pombe the Cfr1 and Bch1 proteins constitute the simplest form of an exomer. Cfr1 co-immunoprecipitates with Assembly Polypeptide adaptor 1 (AP-1), AP-2, and Golgi-localized, gamma-adaptin ear domain homology, ARF-binding (GGA) subunits, and cfr1

Indexed as

Adaptor Protein Complex 1Adaptor Protein Complex 2Adaptor Proteins, Vesicular TransportEndosomesProtein BindingProtein TransportR-SNARE ProteinsSchizosaccharomycesSchizosaccharomyces pombe Proteinstrans-Golgi NetworkAdaptor Protein Complex 1Adaptor Protein Complex 2Adaptor Proteins, Vesicular Transportcfr1 protein, S pombeR-SNARE ProteinsSchizosaccharomyces pombe ProteinsSyb1 protein, S pombeclathrin adaptorsendosomesexomerGolgiyeast

Identifiers

PMID27974503
PMCPMC5289844
OpenAlexW2564643169

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.