Evidence map›Paper›PMID 28003756›Full record

ReviewVascular health and risk management2016

Omega-3 carboxylic acids monotherapy and combination with statins in the management of dyslipidemia.

Lane B Benes, Nikhil S Bassi, Michael H Davidson

Abstract readReview
In one paragraph

Review in Vascular health and risk management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lane B BenesDepartment of Medicine, Section of Cardiology.
Nikhil S BassiDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Michael H DavidsonDepartment of Medicine, Section of Cardiology.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2013 American College of Cardiology/American Heart Association guidelines on cholesterol management placed greater emphasis on statin therapy given the well-established benefits in primary and secondary prevention of cardiovascular disease. Residual risk may remain after statin initiation, in part because of triglyceride-rich lipoprotein cholesterol. Several large trials have failed to show benefit with non-statin cholesterol-lowering medications in the reduction of cardiovascular events. Yet, subgroup analyses showed a benefit in those with hypertriglyceridemia and lower high-density lipoprotein cholesterol level, a high-risk pattern of dyslipidemia. This review discusses the benefits of omega-3 carboxylic acids, a recently approved formulation of omega-3 fatty acid with enhanced bioavailability, in the treatment of dyslipidemia both as monotherapy and combination therapy with a statin.

Indexed as

Biological AvailabilityBiomarkersCarboxylic AcidsCardiovascular DiseasesDrug CompoundingDrug Therapy, CombinationFatty Acids, Omega-3HumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypertriglyceridemiaLipidsRisk FactorsTreatment OutcomeBiomarkersCarboxylic AcidsFatty Acids, Omega-3Hydroxymethylglutaryl-CoA Reductase InhibitorsLipidshypertriglyceridemianon-HDL-Comega-3 carboxylic acidsresidual riskstatin

Identifiers

PMID28003756
PMCPMC5161399

What Socratic holds

Texttitle and abstract
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.