Evidence map›Paper›PMID 28018734›Full record

ArticleBiomedical optics express2016

Classification and analysis of human ovarian tissue using full field optical coherence tomography.

Sreyankar Nandy, Melinda Sanders, Quing Zhu

Abstract read
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The clinical usefulness of optical coherence tomography during cancer interventions.Journal of cancer research and clinical oncology · 2018
    Pooled it
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  14. Quantitative multispectralBiomedical optics express · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sreyankar NandyDepartment of Biomedical Engineering, Washington University in St. Louis, USA.
Melinda SandersUniversity of Connecticut Health Center, Division of Pathology, USA.
Quing ZhuDepartment of Biomedical Engineering, Washington University in St. Louis, USA.

Funding

Co-registered photoacoustic and ultrasound imaging for non-invasive ovarian canR01CA151570 · NCI · WASHINGTON UNIVERSITY · PI BREWER, MOLLY A., ZHU, QUING · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA151570
6 · The paper itself

Abstract

In this study, a full field optical coherence tomography (FFOCT) system was used to analyze and classify normal and malignant human ovarian tissue. 14 ovarian tissue samples (7 normal, 7 malignant) were imaged with the FFOCT system and five features were extracted by analyzing the normalized image histogram from 56 FFOCT images, based on the differences in the morphology of the normal and malignant tissue samples. A generalized linear model (GLM) classifier was trained using 36 images, and sensitivity of 95.3% and specificity of 91.1% was obtained. 20 images were used to test the model, and a sensitivity of 91.6% and specificity of 87.7% was obtained.

Indexed as

(110.4500) Optical coherence tomography(170.1610) Clinical applications(170.3890) Medical optics instrumentation(170.4440) ObGyn(170.6935) Tissue characterization

Identifiers

PMID28018734
PMCPMC5175561

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.