Evidence map›Paper›PMID 28040783›Full record

ArticleG3 (Bethesda, Md.)2017

Polygenic Control of Carotid Atherosclerosis in a BALB/cJ × SM/J Intercross and a Combined Cross Involving Multiple Mouse Strains.

Andrew T Grainger, Michael B Jones, Mei-Hua Chen, Weibin Shi

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle.International journal of molecular sciences · 2021
    Article
  6. Article
  7. Review
  8. Natriuretic Peptide Receptor 2 Locus Contributes to Carotid Remodeling.Journal of the American Heart Association · 2020
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew T GraingerDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908.
Michael B JonesRadiology and Medical Imaging, University of Virginia, Charlottesville, Virginia 22908.
Mei-Hua ChenRadiology and Medical Imaging, University of Virginia, Charlottesville, Virginia 22908.
Weibin ShiDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908 ws4v@virginia.edu.
University of Virginia · US

Funding

Genetic link between type 2 diabetes and atherosclerosisR01DK097120 · NIDDK · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2013 to 2016
$1.4M
H2 haplotype and atherosclerosisR21HL112281 · NHLBI · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2012 to 2013
$414k
NHLBI NIH HHS R21 HL112281NIDDK NIH HHS R01 DK097120
6 · The paper itself

Abstract

Atherosclerosis in the carotid arteries is a major cause of ischemic stroke, which accounts for 85% of all stroke cases. Genetic factors contributing to carotid atherosclerosis remain poorly understood. The aim of this study was to identify chromosomal regions harboring genes contributing to carotid atherosclerosis in mice. From an intercross between BALB/cJ (BALB) and SM/J (SM) apolipoprotein E-deficient (

Indexed as

Genetic Predisposition to DiseaseAnimalsApolipoproteins ECarotid Artery DiseasesCholesterol, HDLComputational BiologyDiet, WesternDisease Models, AnimalGenetic LinkageGenotypeHumansMiceMice, Inbred StrainsMice, KnockoutPhenotypeQuantitative Trait LociApolipoproteins ECholesterol, HDLTriglyceridesdyslipidemiahaplotype analysislinkage mappingplaquevessels

Identifiers

PMID28040783
PMCPMC5295616
OpenAlexW2586969161

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.