Evidence map›Paper›PMID 28054937›Full record

SynthesisNutrients2017

Impact of Probiotic Administration on Serum C-Reactive Protein Concentrations: Systematic Review and Meta-Analysis of Randomized Control Trials.

Mohsen Mazidi, Peyman Rezaie, Gordon A Ferns, Hassan Vatanparast

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 11 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 11 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Biotic Supplements in Patients With Chronic Kidney Disease: Meta-Analysis of Randomized Controlled Trials.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2022
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Mohsen MazidiKey State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. moshen@genetics.ac.cn.
Peyman RezaieBiochemistry and Nutrition Research Centre, School of Medicine, Mashhad University of Medical Science, Mashhad 42536, Iran. peymanrezaie.nutrition@gmail.com.
Gordon A FernsDivision of Medical Education, Brighton and Sussex Medical School, Rm 342, Mayfield House, University of Brighton, Brighton BN1 9PH, UK. s.brown5@brighton.ac.uk.
Hassan VatanparastCollege of Pharmacy and Nutrition, University of Saskatchewan, Health Sciences E-Wing, 104 Clinic Place, Saskatoon, SK S7N 2Z4, Canada. vatan.h@usask.ca.
Brighton and Sussex Medical School · GBChinese Academy of Sciences · CNMashhad University of Medical Sciences · IRSaskatchewan Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted this systematic review and meta-analysis of prospective studies to determine the effect of probiotic administration on serum C-reactive protein (CRP) concentrations. We searched PubMed-Medline, Web of Science, the Cochrane, and Google Scholar databases (until May 2016) to identify prospective studies evaluating the impact of probiotic administration on CRP. We used a random effects models and generic inverse variance methods to synthesize quantitative data, followed by a leave-one-out method for sensitivity analysis. The systematic review registration number was: CRD42016039457. From a total of 425 entries identified via searches, 20 studies were included in the final analysis. The meta-analysis indicated a significant reduction in serum CRP following probiotic administration with a weighted mean difference (WMD) of -1.35 mg/L, (95% confidence interval (CI) -2.15 to -0.55,

Indexed as

C-Reactive ProteinDatabases, FactualHumansInterleukin-10ProbioticsRandomized Controlled Trials as TopicTumor Necrosis Factor-alphaC-Reactive ProteinIL10 protein, humanInterleukin-10Tumor Necrosis Factor-alphaC-reactive proteinmeta-analysisprobiotic

Identifiers

PMID28054937
PMCPMC5295064
OpenAlexW2562877153

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.