SynthesisSports medicine (Auckland, N.Z.)2017
Size Exponents for Scaling Maximal Oxygen Uptake in Over 6500 Humans: A Systematic Review and Meta-Analysis.
Synthesis in Sports medicine (Auckland, N.Z.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 69 citations in OpenAlex.
- Physical Fitness with Exercise and GLP-1 Receptor Agonist Treatment Alone or Combined After Diet-Induced Weight Loss: A Secondary Analysis of a Randomized Controlled Trial in Adults with Obesity.Sports medicine (Auckland, N.Z.) · 2026Trial
- Cardiac output and arteriovenous oxygen difference contribute to lower peak oxygen uptake in patients with fibromyalgia.BMC musculoskeletal disorders · 2023Trial
- Article
- Should we use fat-free mass or body mass and percentage body fat as separate predictors to predict maximum oxygen uptake?BMJ open sport & exercise medicine · 2026Article
- Comment on "Predicting VOSports medicine (Auckland, N.Z.) · 2026Article
- Polygenic prediction of cardiorespiratory fitness in the Trøndelag health study (HUNT).Scientific reports · 2025Article
- Effect of Scaling Peak Oxygen Uptake for Body Size and Composition to Assess Cardiometabolic Risk in Children.Medicine and science in sports and exercise · 2025Article
- Quantifying Running Economy in Amateur Runners: Evaluating VOJournal of sports science & medicine · 2025Article
- Predicting VOSports medicine (Auckland, N.Z.) · 2025Article
- The MDM2 SNP309 differentially impacts cardiorespiratory fitness in young healthy women and men.European journal of applied physiology · 2025Article
- Body composition, maximal fitness, and submaximal exercise function in people with interstitial lung disease.Respiratory research · 2025Article
- Peak Oxygen Consumption Scaled to Body Composition Is Associated With Mortality and Morbidity in People With a Fontan Circulation.Journal of the American Heart Association · 2024Article
- Percentage Predicted Peak Oxygen Consumption in People With Fontan Circulation: A Rapid Systematic Scoping Review and Validation Study.Journal of the American Heart Association · 2024Article
- Allometric exponents for scaling running economy in human samples: A systematic review and meta-analysis.Heliyon · 2024Article
- Cardiopulmonary exercise testing and body composition.ERJ open research · 2024Article
- Interactive effects of intrinsic and extrinsic factors on metabolic rate.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- A generalized equation for predicting peak oxygen consumption during treadmill exercise testing: mitigating the bias from total body mass scaling.Frontiers in cardiovascular medicine · 2024Article
- Skeletal muscle contributions to reduced fitness in cystic fibrosis youth.Frontiers in pediatrics · 2023Article
- Scaling Peak Oxygen Consumption for Body Size and Composition in People With a Fontan Circulation.Journal of the American Heart Association · 2022Article
- Associations of cardiorespiratory fitness, body composition, and blood pressure with arterial stiffness in adolescent, young adult, and middle-aged women.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMaximal oxygen uptake ([Formula: see text]
objectiveThe objective of this systematic review was to provide a quantitative synthesis of reported static allometric exponents used for scaling [Formula: see text]
methodsEight electronic databases (CINAHL, Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, PubMed, Scopus, SPORTDiscus and Web of Science) were searched for relevant studies published up to January 2016. Search terms included 'oxygen uptake', 'cardiorespiratory fitness', '[Formula: see text]
resultsThirty-six studies, involving 6514 participants, met the eligibility criteria. Whole body mass and fat-free mass were used as the scaling denominator in 27 and 15 studies, respectively. The pooled allometric exponent (95% Cls) was found to be 0.70 (0.64 to 0.76) for whole body mass and 0.90 (0.83 to 0.96) for fat-free mass. The between-study heterogeneity was greater for whole body mass (τ = ±0.15) than for fat-free mass (τ = ±0.11). Participant sex explained 30% of the between-study variability in the whole body mass exponent, but the influence on the fat-free mass exponent was trivial. The whole body mass exponent of 0.52 (0.40 to 0.64) for females was substantially lower than the 0.76 (0.70 to 0.83) for males, whereas the fat-free mass exponent was similar for both sexes. The effects of all other moderators were trivial. The 95% PI for fat-free mass ranged from 0.68 to 1.12. The estimated probability of a true fat-free mass exponent in a future study being greater than [Formula: see text] power scaling is 0.98 (very likely) and 0.92 (likely), respectively.
conclusionsIn this quantitative synthesis of published studies involving over 6500 humans, the whole body mass exponent was found to be spuriously low and prone to substantial heterogeneity. We conclude that the scaling of [Formula: see text]
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.