Evidence map›Paper›PMID 28069743›Full record

ArticleMolecular and cellular biology2017

Derepression of the DNA Methylation Machinery of the

Lei Yu, Jun Takai, Akihito Otsuki, Fumiki Katsuoka, Mikiko Suzuki, Saori Katayama, Masahiro Nezu, James Douglas Engel, Takashi Moriguchi, Masayuki Yamamoto

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Lei YuDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Jun TakaiDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Akihito OtsukiDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Fumiki KatsuokaTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Mikiko SuzukiCenter for Radioisotope Sciences, Tohoku University Graduate School of Medicine, Sendai, Japan.
Saori KatayamaDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Masahiro NezuDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
James Douglas EngelDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Takashi MoriguchiDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.
Masayuki YamamotoDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan masiyamamoto@med.tohoku.ac.jp.
Tohoku University · JPUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GATA1 is a critical regulator of erythropoiesis. While the mechanisms underlying the high-level expression of GATA1 in maturing erythroid cells have been studied extensively, the initial activation of the

Indexed as

AnimalsApoptosisBone Marrow CellsCell DifferentiationCell LineageColony-Forming Units AssayDNA (Cytosine-5-)-Methyltransferase 1DNA (Cytosine-5-)-MethyltransferasesDNA MethylationEmbryo, MammalianErythroid CellsErythropoiesisGATA1 Transcription FactorGene Expression ProfilingGene Expression RegulationHaploidyCre recombinaseDNA (Cytosine-5-)-Methyltransferase 1DNA (Cytosine-5-)-MethyltransferasesDnmt1 protein, mouseGATA1 Transcription FactorIntegraseserythropoiesisGata1 gene regulationhematopoietic stem and progenitor cell

Identifiers

PMID28069743
PMCPMC5376630
OpenAlexW2569745354

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.