Evidence map›Paper›PMID 28076869›Full record

ReviewHuman heredity2016

Computational Prediction of the Global Functional Genomic Landscape: Applications, Methods, and Challenges.

Weiqiang Zhou, Ben Sherwood, Hongkai Ji

Abstract readReview
In one paragraph

Review in Human heredity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Weiqiang ZhouDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Md., USA.
Ben Sherwood
Hongkai Ji

Funding

Computational Tools for Mining Large Amounts of ChIP and Gene Expression DataR01HG006282 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI JI, HONGKAI · 2012 to 2016
$2.0M
Statistical and Computational Tools for Next-generation ChIP-seq ApplicationsR01HG006841 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI JI, HONGKAI · 2012 to 2014
$951k
NHGRI NIH HHS R01 HG006282NHGRI NIH HHS R01 HG006841
6 · The paper itself

Abstract

Technological advances have led to an explosive growth of high-throughput functional genomic data. Exploiting the correlation among different data types, it is possible to predict one functional genomic data type from other data types. Prediction tools are valuable in understanding the relationship among different functional genomic signals. They also provide a cost-efficient solution to inferring the unknown functional genomic profiles when experimental data are unavailable due to resource or technological constraints. The predicted data may be used for generating hypotheses, prioritizing targets, interpreting disease variants, facilitating data integration, quality control, and many other purposes. This article reviews various applications of prediction methods in functional genomics, discusses analytical challenges, and highlights some common and effective strategies used to develop prediction methods for functional genomic data.

Indexed as

ChromatinComputational BiologyEpigenesis, GeneticGenomicsHumansModels, GeneticTranscriptomeChromatin

Identifiers

PMID28076869
PMCPMC5599299

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.