ReviewInternational journal of environmental research and public health2017
Mercury Exposure and Heart Diseases.
Review in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 328 citations in OpenAlex.
- Metallomic Dysregulation and Cardiovascular Disease: Essential Trace Elements, Non-essential Metal Exposure, and Heart Failure Risk: A Systematic Review.Cardiovascular toxicology · 2026Pooled it
- Non-essential heavy metal effects in cardiovascular diseases: an overview of systematic reviews.Frontiers in cardiovascular medicine · 2024Pooled it
- Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020Pooled it
- Impact of environmental heavy metal exposure on cardiovascular disease mortality.American journal of preventive cardiology · 2026Article
- Article
- Sustainable Synthesis of Faujasite-Type Zeolites Synthesized from Rice Husk for HgMolecules (Basel, Switzerland) · 2026Article
- Heavy Metal Air Pollution: Human Health Effects and Nanomaterial Strategies for Monitoring and Remediation.Biological trace element research · 2026Review
- The use of minerals, plants and burnt materials in ancient medicine: Approaches to working recipes in John the Physician'sProceedings of the Geologists' Association. Geologists' Association · 2026Article
- Metal carcinogens and cancer: integrating genetic and epigenetic perspectives.Frontiers in oncology · 2026Review
- Emerging inorganic nanomaterial-based electrochemical sensors for heavy metal detection in food: Advances, challenges, and prospects.Current research in food science · 2026Review
- Relative abundance of heavy metal resistance genes of three drinking water treatment plants unveiled through shotgun metagenomics.Frontiers in microbiology · 2026Article
- Association of pre-and postnatal mercury exposure with cardiometabolic risk factors in children: the role of the telomere length and telomerase reverse transcriptase polymorphisms.Environment international · 2025Article
- Chemical Toxicants Used for Food Preservation in Africa. Is it a Case of Ignorance or Food Fraud? A Review.Health science reports · 2025Article
- Diet shifts drive mercury bioaccumulation and distribution in tissues of the longnose lancetfish (Alepisaurus ferox).Marine pollution bulletin · 2025Article
- Mercury toxicity resulting from enzyme alterations- minireview.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Review
- Mercury-Mediated Cardiovascular Toxicity: Mechanisms and Remedies.Cardiovascular toxicology · 2025Review
- Mercury Levels in Selected Medicines and Dietary Supplements in Poland.Biological trace element research · 2025Article
- Heavy metals: toxicity and human health effects.Archives of toxicology · 2025Review
- Biochemical study of the risk of diabetes, prediabetic and insulin resistance in car painters and its association with mercury exposure: a retrospective case-control study.Toxicology research · 2024Article
- Association between heavy metal exposure and biomarkers for non-alcoholic fatty liver disease in Korean adolescents.Heliyon · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental contamination has exposed humans to various metal agents, including mercury. It has been determined that mercury is not only harmful to the health of vulnerable populations such as pregnant women and children, but is also toxic to ordinary adults in various ways. For many years, mercury was used in a wide variety of human activities. Nowadays, the exposure to this metal from both natural and artificial sources is significantly increasing. Recent studies suggest that chronic exposure, even to low concentration levels of mercury, can cause cardiovascular, reproductive, and developmental toxicity, neurotoxicity, nephrotoxicity, immunotoxicity, and carcinogenicity. Possible biological effects of mercury, including the relationship between mercury toxicity and diseases of the cardiovascular system, such as hypertension, coronary heart disease, and myocardial infarction, are being studied. As heart rhythm and function are under autonomic nervous system control, it has been hypothesized that the neurotoxic effects of mercury might also impact cardiac autonomic function. Mercury exposure could have a long-lasting effect on cardiac parasympathetic activity and some evidence has shown that mercury exposure might affect heart rate variability, particularly early exposures in children. The mechanism by which mercury produces toxic effects on the cardiovascular system is not fully elucidated, but this mechanism is believed to involve an increase in oxidative stress. The exposure to mercury increases the production of free radicals, potentially because of the role of mercury in the Fenton reaction and a reduction in the activity of antioxidant enzymes, such as glutathione peroxidase. In this review we report an overview on the toxicity of mercury and focus our attention on the toxic effects on the cardiovascular system.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.