Evidence map›Paper›PMID 28088925›Full record

Trial reportInternational psychogeriatrics2017

A randomized controlled trial of Kundalini yoga in mild cognitive impairment.

Harris A Eyre, Prabha Siddarth, Bianca Acevedo, Kathleen Van Dyk, Pattharee Paholpak, Linda Ercoli, Natalie St Cyr, Hongyu Yang, Dharma S Khalsa, Helen Lavretsky

2 registry-linked trialsOpen access · diamondAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International psychogeriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 9 pooled it
15.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04841668 completedstarted 2021, after this paper: background citation

Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly

Ran2021Enrolled50Registered outcomes51Posted comparisons0ConditionsType 2 Diabetes MellitusArmsMetformin
PMID 8013758PMID 30397356PMID 16443885PMID 11118008PMID 18220635PMID 12086935PMID 28500216PMID 12930161PMID 16219009PMID 11602624PMID 29670545PMID 31330300other papers from this trial
Open the trial in the graph
NCT01983930 nacompletednot on this map

Memory Training Versus Yogic Meditation Training in Older Adults With Mild Cognitive Impairment

TypeinterventionalSponsorUniversity of California, Los AngelesRan2013 to 2016Enrolled81ConditionsMild Cognitive ImpairmentArmsKundalini yoga and meditation, Memory Training
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 9 syntheses or guidelines pooled it, 134 citations in OpenAlex.

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  9. The Effects of Mind-Body Exercise on Cognitive Performance in Elderly: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2018
    Pooled it
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  14. A Randomized Controlled Trial of Tai Chi Chih or Health Education for Geriatric Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
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  20. Clinical Effectiveness of Treatments for Mild Cognitive Impairment in Adults: A Systematic Review.European journal of investigation in health, psychology and education · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Harris A EyreSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Prabha SiddarthSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Bianca AcevedoSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Kathleen Van DykSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Pattharee PaholpakSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Linda ErcoliSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Natalie St CyrSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Hongyu YangSemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Dharma S KhalsaAlzheimer's Research and Prevention Foundation,Tucson,Arizona,USA.
Helen LavretskySemel Institute for Neuroscience and Human Behavior,UCLA,Los Angeles,California,USA.
Alzheimer's Association · USDeakin University · AUKhon Kaen University · TH

Funding

Brain connectivity and response to Tai Chi in geriatric depressionR01AT008383 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LAVRETSKY, HELEN · 2015 to 2019
$4.1M
Methylphenidate Use to Improve Outcomes in Geriatric DepressionR01MH077650 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LAVRETSKY, HELEN · 2008 to 2012
$1.8M
Mentoring and Research in Translational Science of Integrative MedicineK24AT009198 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Helen Lavretsky · 2016 to 2026
$1.4M
Neurobiological Mechanisms of Treatment Response in Geriatric DepressionK24MH086481 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LAVRETSKY, HELEN · 2010 to 2014
$906k
NCCIH NIH HHS K24 AT009198NCCIH NIH HHS R01 AT008383NIMH NIH HHS K24 MH086481NIMH NIH HHS R01 MH077650
6 · The paper itself

Abstract

backgroundGlobal population aging will result in increasing rates of cognitive decline and dementia. Thus, effective, low-cost, and low side-effect interventions for the treatment and prevention of cognitive decline are urgently needed. Our study is the first to investigate the effects of Kundalini yoga (KY) training on mild cognitive impairment (MCI).

methodsOlder participants (≥55 years of age) with MCI were randomized to either a 12-week KY intervention or memory enhancement training (MET; gold-standard, active control). Cognitive (i.e. memory and executive functioning) and mood (i.e. depression, apathy, and resilience) assessments were administered at baseline, 12 weeks and 24 weeks.

resultsAt baseline, 81 participants had no significant baseline group differences in clinical or demographic characteristics. At 12 weeks and 24 weeks, both KY and MET groups showed significant improvement in memory; however, only KY showed significant improvement in executive functioning. Only the KY group showed significant improvement in depressive symptoms and resilience at week 12.

conclusionKY group showed short- and long-term improvements in executive functioning as compared to MET, and broader effects on depressed mood and resilience. This observation should be confirmed in future clinical trials of yoga intervention for treatment and prevention of cognitive decline (NCT01983930).

Indexed as

YogaAffectAgedCaliforniaCognitive DysfunctionExecutive FunctionFemaleHumansLearningMaleMiddle AgedPsychiatric Status Rating ScalesResilience, PsychologicalSeverity of Illness IndexcognitionKirtan KriyaKundalini yogamemory enhancement trainingmild cognitive impairmentmoodresilience

Identifiers

PMID28088925
PMCPMC5540331
OpenAlexW2579377982

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.