Evidence map›Paper›PMID 28092297›Full record

ReviewExercise and sport sciences reviews2017

Vascular Adaptations to Habitual Exercise in Older Adults: Time for the Sex Talk.

Kerrie L Moreau, Cemal Ozemek

Open access · greenAbstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

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  7. Impaired modulation of postjunctional αThe Journal of physiology · 2018
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  14. Effects of regular exercise on vascular function with aging: Does sex matter?American journal of physiology. Heart and circulatory physiology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kerrie L Moreau1Division of Geriatric Medicine, University of Colorado Anschutz Medical Campus, Aurora; 2Denver Veterans Administration Medical Center, Geriatric Research, Education and Clinical Center, Denver, CO; and 3Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL.
Cemal Ozemek
Geriatric Research Education and Clinical Center · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BRYAN C BERGMAN · 1995 to 2026
$32.6M
University of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1M
Biological Mechanisms of Arterial Stiffening With Age and Estrogen DeficiencyR01AG027678 · NIA · UNIVERSITY OF COLORADO DENVER · PI MOREAU, KERRIE · 2006 to 2010
$1.5M
HRT, SERMs and LEG BLOOD FLOW IN POSTMENOPAUSAL WOMENR01AG022241 · NIA · UNIVERSITY OF COLORADO AT BOULDER · PI SEALS, DOUGLAS R · 2004 to 2007
$1.5M
Biological Mechanisms of Vascular Dysfunction with Age and Estrogen DeficiencyR56HL114073 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MOREAU, KERRIE · 2013 to 2013
$651k
HRT and Exercise Effects on Central Arterial ComplianceK01AG020683 · NIA · UNIVERSITY OF COLORADO DENVER · PI MOREAU, KERRIE · 2002 to 2006
$612k
NCATS NIH HHS UL1 TR001082NCRR NIH HHS UL1 RR025780NHLBI NIH HHS R56 HL114073NIA NIH HHS K01 AG020683NIA NIH HHS R01 AG022241NIA NIH HHS R01 AG027678NIA NIH HHS T32 AG000279NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

Regular exercise is promoted as a therapeutic strategy for age-associated endothelial dysfunction. Improvements in endothelial function are observed with endurance exercise in older men, but are diminished or absent in older women. This article examines the hypothesis that sex hormones modulate vascular adaptations to exercise training by influencing antioxidant defense systems, mitochondrial function, oxidative stress, and intracellular signaling.

Indexed as

Adaptation, PhysiologicalAgingCardiovascular DiseasesEndothelium, VascularEstrogensExerciseFemaleGonadal Steroid HormonesHumansMaleSex FactorsEstrogensGonadal Steroid Hormones

Identifiers

PMID28092297
PMCPMC5357172
OpenAlexW2576947518

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.