Evidence mapPaperPMID 28116097Full record

ArticlePharmacology research & perspectives2016

Functional imaging of pharmacological action of SGLT2 inhibitor ipragliflozin via PET imaging using

Keisuke Mitsuoka, Yuka Hayashizaki, Yoshihiro Murakami, Toshiyuki Takasu, Masanori Yokono, Nobuhiro Umeda, Shoji Takakura, Akihiro Noda, Sosuke Miyoshi

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Current Use and Complementary Value of CombiningFrontiers in pharmacology · 2022
    Review
  4. Non-invasive molecular imaging of kidney diseases.Nature reviews. Nephrology · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Keisuke MitsuokaDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Yuka HayashizakiDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Yoshihiro MurakamiDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Toshiyuki TakasuDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Masanori YokonoDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Nobuhiro UmedaDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Shoji TakakuraDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Akihiro NodaDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Sosuke MiyoshiDrug Discovery Research Astellas Pharma Inc. Tsukuba Japan.
Astellas Pharma (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium-dependent glucose cotransporter 2 (SGLT2) is a pharmacological target of type 2 diabetes mellitus. The aim of this study was to noninvasively visualize the pharmacological action of a selective SGLT2 inhibitor ipragliflozin in the kidney using positron emission tomography (PET) imaging with

Indexed as

Ipragliflozin and visualizationMDGPETSGLT2

Identifiers

PMID28116097
PMCPMC5242169
OpenAlexW2467452143

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.